Results 51 to 60 of about 774,930 (257)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Critical Role of Gap Junction Coupled K(ATP)Channel Activity for Regulated Insulin Secretion. [PDF]
PLoS Biology, 2006 Pancreatic beta-cells secrete insulin in response to closure of ATP-sensitive K(+) (K(ATP)) channels, which causes membrane depolarization and a concomitant rise in intracellular Ca(2+) (Ca(i)).
Jonathan V Rocheleau +6 more
doaj +2 more sources
Urban design & urban planning: A critical analysis to the theoretical relationship gap
Ain Shams Engineering Journal, 2021 Over the last 50 years, urban design process has been critiqued in terms of its definitions, principles stakeholders, process and relationship with other disciplines. It has been common that urban design projects turn out different in implementation from
Ahmed S. Abd Elrahman, Moureen Asaad
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Journal of Advanced Transportation, 2018 The operations of multilane roundabouts, especially three-lane roundabouts, are unique and more complicated than any other type of roundabouts. This study aims to analyze driver behavior and estimate the critical gap at three-lane roundabouts. Video data
Khaled Shaaban, Hassan Hamad
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Determinations of critical gap and follow-up time at roundabouts in Jordan
Roads and Bridges, 2019 Critical gap and follow-up times are two important fundamental traffic parameters used in the design and operational analysis of roundabouts and un-signalized intersections.
Nabil Hazim +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
DRIVER AGE DIFFERENCES IN DAY AND NIGHT GAP ACCEPTANCE CAPABILITIES
IATSS Research, 2002 Performance of Two-way Stop-controlled (TWSC) intersections is greatly affected by the gap acceptance capabilities of drivers. However, there have been no detailed studies conducted regarding driver age differences in gap acceptance capabilities under ...
Sunanda DISSANAYAKE, Ph.D.
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source