Results 71 to 80 of about 856,163 (286)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mind the gap! Exploring teachers professional learning needs to cultivate critical data literacies
Formazione & Insegnamento, 2022 Critical Data Literacy as approach to the emergent problem of datafication requires teachers' skills and awareness. However, this professional learning need appears to be overlooked. Our study aims at exploring teachers’ discourses in an attempt to map
Juliana Elisa Raffaghelli +5 more
doaj +1 more source
The compassion gap in UK universities [PDF]
, 2016 Context: This critical reflection is set in the context of increasing marketisation in UK higher education, where students are seen as consumers, rather than learners with power. The paper explores the dark side of academic work and the compassion gap in
Waddington, K.
core +1 more source
DRIVER AGE DIFFERENCES IN DAY AND NIGHT GAP ACCEPTANCE CAPABILITIES
IATSS Research, 2002 Performance of Two-way Stop-controlled (TWSC) intersections is greatly affected by the gap acceptance capabilities of drivers. However, there have been no detailed studies conducted regarding driver age differences in gap acceptance capabilities under ...
Sunanda DISSANAYAKE, Ph.D.
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Measures that can be used to teach critical thinking skills in nurse prescribers [PDF]
, 2006 Critical thinking is a pervasive skill that involves scrutinizing, differentiating, and appraising information and reflecting on the information gained in order to make judgements and inform clinical decisions. Studies inform us of the need for agreement
Banning, M, Maggi Banning
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Frontiers in Neural Circuits, 2016 During development, sensory systems switch from an immature to an adult mode of function along with the emergence of the active cortical states. Here, we used patch-clamp recordings from neocortical slices in vitro to characterize the developmental ...
Fliza eValiullina +9 more
doaj +1 more source