Results 91 to 100 of about 856,163 (286)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Gap-Δenergy, a New Metric of the Bond Energy State, Assisting to Predict Molecular Toxicity [PDF]
Molecular toxicity is a critical feature of drug development. It is thus very important to develop computational models to evaluate the toxicity of small molecules.
Senpeng Zhang (18359694) +2 more
core +1 more source
Dynamic Modeling of VISSIM's Critical Gap Parameter at Unsignalized Intersections [PDF]
, 2013 Critical gaps are essential parameters in the modeling of traffic operations at unsignalized intersections and roundabouts and are the main determinants in the calculation of intersection capacity. In microscopic simulation tools, critical gaps are basic
Tampère, Chris +3 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Social Construction of the Audit Expectation Gap: The Market of Excuses [PDF]
Nous examinons dans cet article l'“audit expectation gap” en nous appuyant sur l'étude de l'évolution des objectifs de l'audit dans le contexte français.
Imen Jedidi, Chrystelle Richard
core
Generation gap in the workplace between Baby Boomers and Generation X [PDF]
, 2001 Plan BGeneration gaps in perspectives, attitudes, and behaviors are nothing new, but they can be difficult to reconcile in the workplace. Lack of attention to generational differences will make any company less efficient; the critical management skills ...
Govitvatana, Wipanut Venique
core
Allergic Diseases and Patient Safety: Bridging a Critical Gap in Clinical Care [PDF]
Patient Safety and Quality Improvement JournalAllergic disorders—ranging from asthma and allergic rhinitis to atopic dermatitis, food allergy, and drug hypersensitivity—affect nearly one-third of the world’s population (1,2).
Farahzad Jabbari Azad
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Pupillometry and filler gap dependencies [PDF]
In this thesis, pupillometry was used to investigate how the parser comprehends filler gap dependencies. It has been shown that the parser automatically searches for and forms dependencies as soon as a gap is encountered.
Fernandez, Leigh
core
Mind the gap? The persistence of pathological discourses in urban regeneration policy [PDF]
, 2010 Urban regeneration policy has historically framed policy problems using a discourse that pathologises areas and spatial communities. Since 2001 in England, and 2002 in Scotland a structural change in policy has occurred where citywide partnerships are ...
Matthews, Peter, Peter Matthews
core +1 more source