Results 81 to 90 of about 856,163 (286)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Temperature dependence of critical currents of two-gap superconductors [PDF]

, 2006
In this paper, we consider the two-gap Ginzburg-Landau (G-L) free energy functional including the interactions, and obtain a very simple and explicit formula which presents the relation between the critical current density and temperature.
H. Şahin, Sahin, H., I. N. Askerzade, Askerzade, I. N.   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Critical mode and band-gap-controlled bipolar thermoelectric properties of SnSe [PDF]

, 2018
From the related article: The reliable calculation of electronic structures and understanding of electrical properties depends on an accurate model of the crystal structure. Here, we have reinvestigated the crystal structure of the high-zT thermoelectric
Loa, Ingo, Popuri, Srinivasa R., Fortes, A. Dominic, Bos, Jan-Willem G.   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Mass gap and finite-size effects in finite temperature SU (2) lattice gauge theory [PDF]

, 1992
Engels J, Mitrjushkin VK. Mass gap and finite-size effects in finite temperature SU (2) lattice gauge theory. Physics Letters, B. 1992;282(3-4):415-422.This letter is devoted to the investigation of the point-point Polyakov loop correlators in SU (2 ...
Engels, Jürgen, Mitrjushkin, V. K.
core   +2 more sources

Pedestrian gap acceptance behavior at unsignalized mid-block crossing under mixed traffic conditions

IATSS Research
In Thailand, 68 % of pedestrian crashes on national highways in 2021 occurred when they were crossing the road. Pedestrians may encounter difficulties when deciding on the minimum safe gap to cross the road under diverse conditions, especially when the ...
Satanan Piyalungka, Kunnawee Kanitpong, Ampol Karoonsoontawong   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Gender(ed) Gap(s) in STEM : Explaining the persistent underrepresentation of women in STEM careers [PDF]

, 2023
Countless projects and campaigns have sought to increase the number of women in STEM (Science, Technology, Engineering, Mathematics) in recent decades. Nevertheless, women continue to be underrepresented in STEM education and workforce, particularly
Bairoh, Susanna
core