Results 241 to 250 of about 8,191,239 (342)
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Integrating UpToDate with case-based learning enhances residents' clinical decision-making and training satisfaction in critical care training. [PDF]
Zhang D, Sun W, Lu X.
europepmc +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Pulmonary function and airflow limitation in bronchiectasis: a case-control study of two independent cohorts. [PDF]
Jeon DS +9 more
europepmc +1 more source
Critical Numbers for Restricted Sumsets: Rigidity and Collapse in Finite Abelian Groups [PDF]
Bocong Chen, Jing Huang
openalex
Development of group theory textbook with podcast learning which connected to the school mathematics content and critical thinking skills [PDF]
Rina Dwi Setyawati +6 more
openalex +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Exploring Intensive Care Nurses' Experiences and Perceptions of Patients With a Co-Morbid Mental Health Disorder. [PDF]
Teece A, Baker J.
europepmc +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

