Results 101 to 110 of about 6,200,707 (327)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Minor Planet (121) Hermione: A Critical Test of the Berkeley Tables of Perturbations by Jupiter for the Hecuba Group [PDF]
, 1934 Sophia H. Levy
openalex +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
The Perception of Critical Success Factors for PPP Projects in Different Stakeholder Groups
Entrepreneurial Business and Economics Review, 2016 Objective: The main goal of the research is to enhance understanding which factors are perceived as critical for the success of public-private partnerships (PPPs) by different stakeholder groups on different stages of the project life cycle.
Joanna Węgrzyn
doaj +1 more source
A Critical Examination of Pascal's Value for the Magnetic Susceptibility of the CH2-group. [PDF]
, 1936 S. S. BHATNAGAR, N. G. MITRA
openalex +1 more source
Dowling group geometries and the critical problem
Journal of Combinatorial Theory, Series B, 1989 This paper relates the critical problem of Crapo and Rota to Dowling group geometries. If A is a finite group, \(Q_ r(A)\) is the rank r Dowling group geometry over A and M is a rank r matroid embeddable as a minor of \(Q_ r(A)\), then it is shown that the critical exponent of M over A is well defined and is determined by an evaluation of the ...
openaire +3 more sources
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Research of Intersection Groups Optimization Control Method Based on Critical Path Identification
MATEC Web of Conferences, 2018 An optimal intersection groups control method based on critical path identification is proposed. The control algorithm uses a binary search to gradually determine the scope of the intersection groups, uses the duality method to express the intersection ...
Liu Ying, Fang Lv, Shen Jiayan
doaj +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source