Results 181 to 190 of about 2,498,418 (268)

Mapping critical raw material flows in Belgium: focus on Platinum Group Metals (PGM) and nickel

Dirk Nelen
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Age-Specific Prognostic Models for Sepsis-Associated Acute Kidney Injury: A Multicenter Cohort Study. [PDF]

Med Sci Monit
Jin J, Xiang M, Meng J, Peng J.
europepmc   +1 more source

Tensor renormalization group approach to critical phenomena via symmetry-twisted partition functions

Shinichiro Akiyama, Raghav G. Jha, Jun Maeda, Yuya Tanizaki, Judah Unmuth-Yockey   +4 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Correction: Discarded intravenous medication in the ICU: the GAME-OVER multicenter prospective observational study. [PDF]

Crit Care
d'Aranda E, GAME-OVER investigators group, Pons S, Chelly J, Atchade E, Bonnet L, SFAR Sustainable Development Committee, Dahyot-Fizelier C, SFAR Critical Care Committee, Kamel T, Giannoni F, Collange O, Besnier E, Schoeffler M, Mayeur N, Quere PL, Marecal L, Pernod C, Geay C, Esnault P, Cinotti R, SFAR Research Network, Cesana M, Cungi PJ.   +23 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Association Between Abnormal DNA Methylation and Altered Transcriptome in Muscle Five Years After Critical Illness. [PDF]

J Cachexia Sarcopenia Muscle
Uzun Ayar C, Güiza F, Derese I, Van den Berghe G, Vanhorebeek I.   +4 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Enhancing care in alcohol-associated liver disease through peer support for alcohol use disorder. [PDF]

Hepatol Commun
Jones J, Gray-Davis L, Leggio L, DiMartini A, Liangpunsakul S.   +4 more
europepmc   +1 more source