Results 141 to 150 of about 15,857,552 (384)

Fibroblast Growth Factor 23 Associates with Death in Critically Ill Patients [PDF]

, 2018
David E. Leaf, Edward D. Siew, Michele F. Eisenga, Karandeep Singh, Finnian R. Mc Causland, Anand Srivastava, T. Alp İkizler, Lorraine B. Ware, Adit A. Ginde, John A. Kellum, Paul M. Palevsky, Myles Wolf, Sushrut S. Waikar   +12 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

On Kirchhoff-Schrödinger-Poisson-type systems with singular and critical nonlinearity

Advances in Nonlinear Analysis
This work focuses on the Kirchhoff-Schrödinger-Poisson-type system with singular term and critical Sobolev nonlinearity as follows: −a+b∫Ω∣∇u∣pdxΔpu+ϕ∣u∣q−2u=λu−γ+∣u∣p∗−2uinΩ,−Δϕ=∣u∣qinΩ,u=ϕ=0on∂Ω,\left\{\begin{array}{ll}-\left(a+b\mathop{\displaystyle ...
Yang Baoling, Zhang Deli, Liang Sihua
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

On general Kirchhoff type equations with steep potential well and critical growth in $ \mathbb{R}^2 $

AIMS Mathematics
In this paper, we study the following Kirchhoff-type equation:$ \begin{equation*} M\left(\displaystyle{\int}_{\mathbb{R}^2}(|\nabla u|^2 +u^2)\mathrm{d} x\right)(-\Delta u+u) + \mu V(x)u = K(x) f(u) \ \ \mathrm{in} \ \ \mathbb{R}^2, \end{equation ...
Zhenluo Lou , Jian Zhang
doaj   +1 more source

Critical periods of growth [PDF]

Proceedings of the Nutrition Society, 1976
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Solutions to singular quasilinear elliptic equations on bounded domains

Electronic Journal of Differential Equations, 2018
In this article we study quasilinear elliptic equations with a singular operator and at critical Sobolev growth. We prove the existence of positive solutions.
Zhouxin Li, Youjun Wang
doaj  

Estimating the critical points of an epidemic: An application of non-epidemiological logistic growth model for COVID-19 [PDF]

, 2020
Ivan Bezerra Allaman, Enio Galinkin Jelihovschi   +1 more
openalex   +1 more source