Results 71 to 80 of about 11,870,254 (353)

Groundstates for Choquard type equations with weighted potentials and Hardy–Littlewood–Sobolev lower critical exponent

open access: yesAdvances in Nonlinear Analysis, 2021
We are concerned with a class of Choquard type equations with weighted potentials and Hardy–Littlewood–Sobolev lower critical ...
Zhou Shuai, Liu Zhisu, Zhang Jianjun
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

SUPER-CRITICAL GROWTH OF MASSIVE BLACK HOLES FROM STELLAR-MASS SEEDS [PDF]

open access: yes, 2014
We consider super-critical accretion with angular momentum onto stellar-mass black holes as a possible mechanism for growing billion-solar-mass black holes from light seeds at early times. We use the radiatively inefficient “slim disk” solution—advective,
P. Madau, F. Haardt, M. Dotti
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Existence of standing wave solutions for coupled quasilinear Schrödinger systems with critical exponents in $\mathbb{R}^N$

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2017
This paper is concerned with the following quasilinear Schrödinger system in $\mathbb{R}^N$: \begin{equation*} \begin{cases} -\varepsilon^2\Delta u+V_1(x)u-\varepsilon^2\Delta(u^{2})u=K_1(x)|u|^{22^*-2}u+h_1(x,u,v)u, \\ -\varepsilon^2\Delta v+V_2(x)v ...
Lili Wang, Xiangdong Fang, Zhi-Qing Han
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Concentration results for a magnetic Schrödinger-Poisson system with critical growth

open access: yesAdvances in Nonlinear Analysis, 2020
This paper is concerned with the following nonlinear magnetic Schrödinger-Poisson type ...
Liu Jingjing, Ji Chao
doaj   +1 more source

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