Results 91 to 100 of about 5,391,473 (290)

Ground-state solutions of a Hartree–Fock type system involving critical Sobolev exponent

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, ground-state solutions to a Hartree–Fock type system with a critical growth are studied. Firstly, instead of establishing the local Palais–Smale (P.-S.) condition and estimating the mountain-pass critical level, a perturbation method is ...
Xiaoli Zhu, Zushun Min
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Uniform L ∞-boundedness for solutions of anisotropic quasilinear systems

Advanced Nonlinear Studies
In this paper we obtain uniformly locally L ∞-estimate of solutions to non-autonomous quasilinear system involving operators in divergence form and a family of nonlinearities that are allowed to grow also critically.
Borgia Natalino, Cingolani Silvia, Vannella Giuseppina   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Existence results for critical growth Kohn-Laplace equations with jumping nonlinearities

Demonstratio Mathematica
This article is concerned with the existence of nontrivial solutions to critical growth Kohn-Laplace equations with jumping nonlinearities. Or, more specifically, we consider the following Kohn-Laplace problem: −ΔHu=bu+−au−+∣u∣Q∗−2u,inΩ,u=0,on∂Ω,\left ...
An Yu-Cheng, Tian Guai-Qi, An Bi-Jun
doaj   +1 more source

Ground state solutions for Kirchhoff-type equations with a general nonlinearity in the critical growth

Advances in Nonlinear Analysis, 2018
In this paper, we concern ourselves with the following Kirchhoff-type equations:
Xu Li-Ping, Chen Haibo
doaj   +1 more source

Ground states for a fractional scalar field problem with critical growth

, 2016
We prove the existence of a ground state solution for the following fractional scalar field equation $(-\Delta)^{s} u= g(u)$ in $\mathbb{R}^{N}$ where $s\in (0,1), N> 2s$,$ (-\Delta)^{s}$ is the fractional Laplacian, and $g\in C^{1, \beta}(\mathbb{R ...
Ambrosio, Vincenzo
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source