Results 71 to 80 of about 11,486,155 (229)

Ground-state solutions of a Hartree–Fock type system involving critical Sobolev exponent

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, ground-state solutions to a Hartree–Fock type system with a critical growth are studied. Firstly, instead of establishing the local Palais–Smale (P.-S.) condition and estimating the mountain-pass critical level, a perturbation method is ...
Xiaoli Zhu, Zushun Min
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Uniform L ∞-boundedness for solutions of anisotropic quasilinear systems

Advanced Nonlinear Studies
In this paper we obtain uniformly locally L ∞-estimate of solutions to non-autonomous quasilinear system involving operators in divergence form and a family of nonlinearities that are allowed to grow also critically.
Borgia Natalino, Cingolani Silvia, Vannella Giuseppina   +2 more
doaj   +1 more source

Growth through Diversification in Hermosillo

In this report, we study Hermosillo’s economic performance and assess critical issues affecting the city’s ability to achieve stronger economic growth.
Bustos, Sebastian, O'Brien, Timothy, Shah, Taimur, Lamby, Lucas, Barrios, Douglas, Fortunato, Andres, Arcay Finlay, Guillermo, Hausmann, Ricardo, Daboin Pacheco, Jesus   +8 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Multiple solutions for a nonhomogeneous quasilinear sub-elliptic system with critical growth and logarithmic perturbation

Demonstratio Mathematica
The interest of this paper is that we use the critical point theory to prove the existence of a sequence of non-trivial solutions for a class of nonhomogeneous quasilinear Sub-elliptic systems with critical growth and logarithmic perturbation.
An Yu-Cheng, An Bi-Jun
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Existence results for critical growth Kohn-Laplace equations with jumping nonlinearities

Demonstratio Mathematica
This article is concerned with the existence of nontrivial solutions to critical growth Kohn-Laplace equations with jumping nonlinearities. Or, more specifically, we consider the following Kohn-Laplace problem: −ΔHu=bu+−au−+∣u∣Q∗−2u,inΩ,u=0,on∂Ω,\left ...
An Yu-Cheng, Tian Guai-Qi, An Bi-Jun
doaj   +1 more source

Ground state solutions for Kirchhoff-type equations with a general nonlinearity in the critical growth

Advances in Nonlinear Analysis, 2018
In this paper, we concern ourselves with the following Kirchhoff-type equations:
Xu Li-Ping, Chen Haibo
doaj   +1 more source