Results 81 to 90 of about 16,071,502 (380)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Complexity and Criticality in Laplacian Growth Models [PDF]
7pages.
Guinea, F., Pla, O., Louis, E.
openaire +2 more sources
Supplementary Figure Legends 1-4 from Retinoblastoma Family Proteins Have Distinct Functions in Pulmonary Epithelial Cells <i>In vivo</i> Critical for Suppressing Cell Growth and Tumorigenesis [PDF]
David S. Simpson +3 more
openalex +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Managing the transition to critical green growth: The ‘Green Growth State’ [PDF]
Political will at the national and multilateral scale is coalescing around the emerging discourse of Green Growth. The narratives and practices of Green Growth have already been rejected by many stakeholders as a reformulation of business as usual discourse.
Vazquez-Brust, Diego +2 more
openaire +2 more sources
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Fractional elliptic systems with nonlinearities of arbitrary growth
In this article we discuss the existence, uniqueness and regularity of solutions of the following system of coupled semilinear Poisson equations on a smooth bounded domain $\Omega$ in $\mathbb{R}^n$: $$\displaylines{ \mathcal{A}^s u= v^p \quad\text ...
Edir Junior Ferreira Leite
doaj
An exhaustive numerical investigation of the growth of magnetic films in confined $(d+1)$-dimensional stripped geometries ($d=1,2$) is carried out by means of extensive Monte Carlo simulations.
Aarão Reis +55 more
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source

