Results 81 to 90 of about 16,071,502 (380)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Complexity and Criticality in Laplacian Growth Models [PDF]

open access: yesEurophysics Letters (EPL), 1993
7pages.
Guinea, F., Pla, O., Louis, E.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Managing the transition to critical green growth: The ‘Green Growth State’ [PDF]

open access: yesFutures, 2014
Political will at the national and multilateral scale is coalescing around the emerging discourse of Green Growth. The narratives and practices of Green Growth have already been rejected by many stakeholders as a reformulation of business as usual discourse.
Vazquez-Brust, Diego   +2 more
openaire   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Fractional elliptic systems with nonlinearities of arbitrary growth

open access: yesElectronic Journal of Differential Equations, 2017
In this article we discuss the existence, uniqueness and regularity of solutions of the following system of coupled semilinear Poisson equations on a smooth bounded domain $\Omega$ in $\mathbb{R}^n$: $$\displaylines{ \mathcal{A}^s u= v^p \quad\text ...
Edir Junior Ferreira Leite
doaj  

Order-disorder criticality, wetting, and morphological phase transitions in the irreversible growth of far-from-equilibrium magnetic films

open access: yes, 2002
An exhaustive numerical investigation of the growth of magnetic films in confined $(d+1)$-dimensional stripped geometries ($d=1,2$) is carried out by means of extensive Monte Carlo simulations.
Aarão Reis   +55 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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