Results 31 to 40 of about 59,671 (267)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Silver nanorod-induced porous networks: A pathway to efficient thermal energy transfer via pool boiling heat transfer

Case Studies in Thermal Engineering, 2023
With the continuous trend of miniaturization in the electronics sector, high heat flux management is becoming increasingly important for ensuring efficient and safe operation.
Nurettin Sezer, Shoukat Alim Khan, Yusuf Biçer, Muammer Koç   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Critical Heat Flux in Nanofluids at Quasi-Stationary and Stepwise Heat Generation

MATEC Web of Conferences, 2016
In this paper results of an experimental study on critical heat flux in nanofluid at quasi-stationary and stepwise heat generation are presented. Freon R21 with addition of 0.0077 vol.% of SiO2 nanoparticles was used as test fluid.
Moiseev Mikhail, Zhukov Vladimir, Kuznetsov Denis   +2 more
doaj   +1 more source

Study on critical heat flux density at the quasi-stationary heating of superficially boiling binary mixtures

Advanced Engineering Research, 2015
The heat-flow rate and temperature of the heater are measured at various liquid subcooling boiling points. An experimental plant and the obtained results on the heat energy motion in the superficially boiling binary liquid mixtures are described.
Victor Vladimirovich Kozhokaru, Evgeny Vasilyevich Lykov   +1 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Experimental Study of Carbon Dioxide Boiling Crisis in Near-critical Natural Circulation

Yuanzineng kexue jishu
Carbon dioxide is utilized as a direct coolant in micro-modular gas-cooled fast reactor cycle systems. The supercritical carbon dioxide cycle systems are attracted widespread attention for their compact design and high operating efficiency.
ZENG Chengtian1, ZHOU Yuan1, HUANG Yanping2, LUO Qiao1, TIAN Gengyuan1, HUANG Jiajian1
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Experimental study of bubble behaviors and CHF on printed circuit board (PCB) in saturated pool water at various inclination angles

Nuclear Engineering and Technology, 2018
Experiments were performed to investigate bubble behaviors and pool boiling Critical Heat Flux (CHF) on a thin flat rectangular copper heater fabricated on Printed Circuit Board (PCB), at various inclination angles. The surface inclination angles were 0°,
Elvira F. Tanjung, Bernard O. Alunda, Yong Joong Lee, Daeseong Jo   +3 more
doaj   +1 more source