Results 111 to 120 of about 5,699,579 (389)
A case report of classic galactosemia with a GALT gene variant and a literature review
BMC PediatricsBackground Galactosemia is an autosomal recessive disorder resulting from an enzyme defect in the galactose metabolic pathway. The most severe manifestation of classic galactosemia is caused by galactose-1-phosphate uridylyltransferase (GALT) deficiency,
Yong-cai Wang +5 more
doaj +1 more source
Remarks on the Prandtl Equation [PDF]
arXiv, 2011 In a recent result of Gerard-Varet and Dormy [5], they established ill-posedness for the Cauchy problem of the linearized Prandtl equation around non-monotic special solution which is independent of x and satisfies the heat equation. In [6] and [7], some nonlinear ill-posedness were established with this counterexample.
arxiv
The microbiome and critical illness [PDF]
The Lancet Respiratory Medicine, 2016 The central role of the microbiome in critical illness is supported by a half century of experimental and clinical study. The physiological effects of critical illness and the clinical interventions of intensive care substantially alter the microbiome.
openaire +3 more sources
Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying functional measures that are both valid and reliable in the limb girdle muscular dystrophy (LGMD) population is critical for quantifying the level of functional impairment related to disease progression in order to establish clinical trial readiness in the context of anticipated therapeutic trials.
Stephanie M. Hunn +29 more
wiley +1 more source
Defining persistent critical illness based on growth trajectories in patients with sepsis
Critical Care, 2020 Background Persistent critical illness is common in critically ill patients and is associated with vast medical resource use and poor clinical outcomes.
Wentao Bao +4 more
semanticscholar +1 more source
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Arthritis Care &Research, EarlyView.Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp +6 more
wiley +1 more source
Circadian Gene Expression Rhythms During Critical Illness.
Critical Care Medicine, 2020 OBJECTIVES Core clock genes regulate tissue-specific transcriptome oscillations that synchronize physiologic processes throughout the body, held in phase by the central circadian rhythm. The central circadian rhythm rapidly dampens with onset of critical
Matthew B. Maas +5 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective The increasing burden associated with low back pain (LBP) is a critical issue. This is a novel analysis of trends in risk factors for LBP aiming to identify risk factors that require further attention or consideration in global policies to reduce the burden of LBP.
Katharine E. Roberts +5 more
wiley +1 more source
Frontiers in Immunology, 2018 Sepsis is characterized by injury of pulmonary microvascular endothelial cells (PMVEC) leading to barrier dysfunction. Multiple mechanisms promote septic PMVEC barrier dysfunction, including interaction with circulating leukocytes and PMVEC apoptotic ...
Lefeng Wang +13 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Promoting Resilience in Stress Management (PRISM) is a resilience coaching program designed for adolescents with chronic illness. We aimed to examine the perceived feasibility, acceptability, and appropriateness of PRISM among pediatric rheumatologists treating adolescents with chronic musculoskeletal pain and obtain recommendations for ...
Sabrina Gmuca +9 more
wiley +1 more source