Results 111 to 120 of about 5,642,725 (257)

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

Advanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine, Arianna Skirzynska, Allysia A. Chin, Julie Audet, Molly S. Shoichet   +4 more
wiley   +1 more source

Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness

Frontiers in Immunology
IntroductionDespite continued improvement in post-sepsis survival, long term morbidity and mortality remain high. Chronic critical illness (CCI), defined as persistent inflammation and organ injury requiring prolonged intensive care, is a harbinger of ...
Evan L. Barrios, Leandro Balzano-Nogueira, Valerie E. Polcz, Christine Rodhouse, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Shawn D. Larson, Ashish Sharma, Gilburt Upchurch, Shannon M. Wallet, Todd M. Brusko, Todd M. Brusko, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Rhonda Bacher, Rhonda Bacher, Guoshuai Cai, Michael P. Kladde, Clayton E. Mathews, Lyle L. Moldawer, Maigan A. Brusko, Maigan A. Brusko, Philip A. Efron   +27 more
doaj   +1 more source

Intensive care diaries reduce new onset post traumatic stress disorder following critical illness: a randomised, controlled trial

, 2010
Patients recovering from critical illness have been shown to be at risk of developing Post Traumatic Stress disorder (PTSD). This study was to evaluate whether a prospectively collected diary of a patient's intensive care unit (ICU) stay when used during
Bäckman, Carl, Jones, Christina, Granja, Cristina, Capuzzo, Maurizia, Egerod, Ingrid, Griffiths, Richard D, Flaatten, Hans, Rylander, Christian,   +7 more
core  

Facial nerve involvement in critical illness polyneuropathy

, 2010
Although ICU-acquired neuromuscular weakness is a well-known problem, critical illness neuropathy is an under-diagnosed entity in critically ill patients. Facial musculature is typically not involved in critical illness neuropathy. This report highlights
Arvind K Baronia, ArvindK Baronia, Mohan Gurjar, Banani Poddar, Afzal Azim   +4 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source

Update on disseminated cryptococcosis in non-HIV infected children

Italian Journal of Pediatrics
Background Disseminated cryptococcosis is a rare disease in children, especially in children with normal immunity. The understanding of this disease needs to be improved.
Xiao-bo Zhang, Huiying Lin, Xiao Wu, Guang-min Nong   +3 more
doaj   +1 more source

Descriptor‐Informed Screening of Interface‐Active Molecules for Efficient Magnesium Metal Anodes

Advanced Materials, EarlyView.
A descriptor‐informed molecular screening strategy identifies 4‐bromo‐N, N‐dimethylaniline (BrNNA) as an interface‐active electrolyte component that enables fast Mg stripping/plating in Mg(TFSI)2‐based electrolytes. By simultaneously regulating Mg2+ solvation and interphase formation, the BrNNA‐containing electrolyte delivers activation‐free Mg ...
Hao Xu, Yue Li, Tian Xie, Arafat Hossain Khan, Fengzhan Sun, Zhao Li, Lingyue Liu, Zhaohui Yang, Xinlong Xie, Huayu Qiu, Quanquan Guo, Tian Sun, Xingyuan Chu, Jingwei Du, Jianxin Zou, Xinliang Feng, Minghao Yu   +16 more
wiley   +1 more source

Tocilizumab is associated with reduced delirium and coma in critically ill patients with COVID-19

Scientific Reports
Recent preclinical studies demonstrate a direct pathological role for the interleukin-6 (IL-6) pathway in mediating structural and functional delirium-like phenotypes in animal models of acute lung injury.
Tuqa Alkhateeb, Joanna L. Stollings, Ine Sohn, Dandan Liu, L. Montana Fleenor, E. Wesley Ely, Shouri Lahiri   +6 more
doaj   +1 more source