Results 171 to 180 of about 5,699,579 (389)

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

The role of albumin in critical illness [PDF]

, 2000
John Nicholson, Morné Wolmarans, G.R. Park   +2 more
openalex   +1 more source

Immunity Debt for Seasonal Influenza After the COVID‐19 Pandemic and as a Result of Nonpharmaceutical Interventions: An Ecological Analysis and Cohort Study

Advanced Science, EarlyView.
This study provides support for the immunity debt hypothesis, revealing a 131.72% increase in influenza rates during winter and a 161.23% rise in summer, 1 year following the global easing of COVID‐19 restrictions. This study offers empirical evidence of immunity debt on a global level, highlighting the importance of incorporating this concept into the
Li Chen, Yuchen Guo, Kim López‐Güell, Jun Ma, Yanhui Dong, Junqing Xie, Daniel Prieto Alhambra   +6 more
wiley   +1 more source

Factors associated with antibiotic resistance and survival analysis of severe pneumonia patients infected with , , and : A retrospective cohort study in Jakarta, Indonesia

SAGE Open Medicine
Background: Antimicrobial resistance is one of the most significant challenges to global public health and the risk factors in severe pneumonia are constantly growing.
Gurmeet Singh, Tonny Loho, Mira Yulianti, Dita Aditianingsih, Laila Fakhriyatuz Zakiyah, Sudirman Fakhruddin Masse, Muhammad Rizki Triono   +6 more
doaj   +1 more source

Susceptibility to critical illness: reserve, response and therapy [PDF]

, 2000
Julian Bion
openalex   +1 more source

From De Novo Conceived Small Molecules to Multifunctional Supramolecular Nanoparticles: Dual Biofilm and T3SS Intervention, Enhanced Foliar Affinity, and Effective Rice Disease Control

Advanced Science, EarlyView.
From de novo engineered bioactive molecules BtP27 to the multifunctional supramolecular material BtP27@β‐CD with a sunflower‐shaped morphology: its pragmatic applications in augmenting foliar affinity, disrupting biofilms and T3SS, and managing rice pathologies. Abstract Conventional antimicrobials typically exhibit suboptimal deposition on rice leaves,
Xianfu Mu, Kongjun Liu, Jinghan Yang, Juan Liu, Fengpei Du, Gefei Hao, Peiyi Wang   +6 more
wiley   +1 more source

Early signs of critical illness polyneuropathy in ICU patients with systemic inflammatory response syndrome or sepsis [PDF]

, 2000
A. Tennilä, Tapani Salmi, Ville Pettilä, RistoO. Roine, Tero Varpula, O. Takkunen   +5 more
openalex   +1 more source

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

Advanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy, Bo Zhao, Ajda Lenardič, Huyen Thuc Tran Luong, Ori Bar‐Nur, Johan Auwerx, Martin Wohlwend   +6 more
wiley   +1 more source

The IES-R remains a core outcome measure for PTSD in critical illness survivorship research

Critical Care, 2019
Megan M. Hosey, O. Joseph Bienvenu, Victor D. Dinglas, Alison E. Turnbull, Ann M. Parker, Ramona O. Hopkins, Karin J. Neufeld, Dale M. Needham   +7 more
doaj   +1 more source

Pseudo-Locked-In Syndrome and Apnea Due to Critical Illness Myopathy

, 1970
Selena Au, Darrel Cotton, Andreas Krämer, Jeffery Joseph   +3 more
openalex   +2 more sources