Results 171 to 180 of about 5,642,725 (257)

Sleep physiology and critical illness: A narrative review. [PDF]

J Intensive Care Soc
Welbourne J.
europepmc   +1 more source

Anion‐Driven Surface Reconstruction Enables Direct Regeneration of LiCoO2 Cathode Material

Advanced Science, EarlyView.
The anion scpecies in molten salt systems critically govern the surface reconstruction of regenerated LiCoO2. LiOH−LiCl flux, featuring strong Cl− adsorption and facile dissociation, directs preferential relithiation on (003) facets and forms a Li−O enriched interface.
Mengting Zheng, Shangshu Qian, Meng Li, Shanqing Zhang, Jun Lu   +4 more
wiley   +1 more source

Standard of care for rehabilitation in critical illness. [PDF]

Intensive Care Med
Hodgson CL, Ayre E, Broadley T, Burry L, Casey K, Dale C, Eggmann S, Freeman-Sanderson A, Kho ME, Paton M, Ridley EJ, Rose L, Schaller SJ, Herridge MS.   +13 more
europepmc   +1 more source

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source

Post-intensive care syndrome after critical illness: a reply. [PDF]

Anaesthesia
Oh TK, Song IA.
europepmc   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Critical Episodes of Inflammation, Catabolism, and Immunosuppression Define Mortality Risk in Chronic Critical Illness. [PDF]

J Clin Med
Likhvantsev V, Berikashvili L, Polyakov P, Yadgarov M, Yakovlev A, Grechko A.   +5 more
europepmc   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source

Gut microecology in critical illness: mechanisms, biomarkers, and therapeutic strategies - a critical appraisal. [PDF]

Front Gastroenterol (Lausanne)
Tian L, Xu S, Xie X, Wang M, Huang L.
europepmc   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source