Results 211 to 220 of about 5,642,725 (257)

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Life-sustaining therapy limitation in critical illness: unequal weights of demographics, disease severity, and comorbidities. [PDF]

Crit Care Sci
Ribeiro GLH, Ramos JGR, Rodrigues Filho EM, Teixeira C.   +3 more
europepmc   +1 more source

Data‐Driven and Physics‐Informed Modeling Perspectives for Soft Manipulators: From SINDy to Hybrid Intelligence

Advanced Science, EarlyView.
This Perspective charts the modeling landscape for soft manipulators, spanning sparse system identification, neural dynamics, physics‐informed models and hybrid intelligence. We examine how physics, data, sensing, adaptation and control can assume complementary roles within this landscape, and provide a framework for selecting modeling approaches ...
Wenbo Hui, Yunyi Wang, Teng Zhang, Yang Chen, Min Pan   +4 more
wiley   +1 more source

Remote Multicomponent Rehabilitation and Cost-Effectiveness in Survivors of Critical Illness.

JAMA Netw Open
Zanganeh M, O'Neill B, Bradley JM, Connolly B, Bruce J, Underwood M, Ratna M, Lall R, Ji C, Costley J, Clarke R, Dark P, Duffy O, Firshman P, Hart ND, Henderson A, Jones K, Kenyon R, Murphy D, Perkins GD, Raynes K, Terblanche E, McAuley DF, Madan J, iRehab Trial Investigators.   +24 more
europepmc   +1 more source

Sex and gender differences in hemostasis in critical illness. [PDF]

Crit Care Sci
Helms J, Juffermans NP, Iba T.
europepmc   +1 more source

Pyrolyzed Photoresist as a Continuous‐Tone Mask for Grayscale Lithography

Advanced Science, EarlyView.
True grayscale contact photolithography masks are created by pyrolysis of 3D multiphoton resist patterns. The resulting carbon masks retain micrometer‐scale patterned features while providing continuous‐tone optical transmission. This approach provides access to high‐quality grayscale lithography without requiring exotic materials or commercial mask ...
Tielyr D. Creason, Gavin C. Gee, Zachary T. Piontkowski, Toai Ton‐That, Robert Reyna, Edward R. Arata, Mason Risley, Jacob D. Boissiere, Bryan Kaehr, D. Bruce Burckel   +9 more
wiley   +1 more source

Genetic Variability of <i>IFNAR2</i> Gene and Risk of COVID-19 Critical Illness Among the Tunisian Population. [PDF]

Viruses
Azri A, Althumairy DA, Memni H, Almalki MA, Hadj Hassine I, Chatti N, Gharbi J, Ben M'hadheb M.   +7 more
europepmc   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source

Gut Failure During Pediatric Critical Illness: Toward a Phenotype-Driven Framework for Early Recognition, Prognostication, and Prevention. [PDF]

Children (Basel)
Mansour M, Valenzuela MT, Knebusch N, Coss-Bu JA, Typpo KV.   +4 more
europepmc   +1 more source

ReLink: Reliable Deep Learning for Microscopic Motion Tracking

Advanced Science, EarlyView.
ReLink enables reliable trajectory linking in single‐particle tracking by integrating physics‐informed motion statistics with confidence‐based adaptive filtering. Across diverse simulated and experimental conditions, ReLink robustly reconstructs trajectories and preserves the fidelity of downstream analyses, enabling accurate characterization of ...
Yuan Jiang, Xiaochen Feng, Hongda Wei, Hao Sha, Hongpeng Wang, Min Zhang, Sanyang Han, Yongbing Zhang   +7 more
wiley   +1 more source