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Anemia in the critically ill

Critical Care Clinics, 2004
The anemia of critical illness is a distinct clinical entity with characteristics similar to that of chronic disease anemia. Several solutions to the processes of anemia, such as blunted erythropoietin production and erythropoietin response and abnormalities in iron metabolism have been developed.
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Ghrelin in Critical Illness

American Journal of Respiratory Cell and Molecular Biology, 2015
Abstract Ghrelin, a recently described peptide, has attracted significant attention in recent years, primarily in the context of its endocrine- and appetite-regulating effects. The versatility of this peptide is manifested in a rapidly expanding body of literature highlighting its nonendocrine functions.
Tathagat Narula, Bennett P. deBoisblanc
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Anemia of Critical Illness

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2008
Anemia of critical illness, a commonly encountered clinical situation, is hematologically similar to that of chronic anemia, except that the onset is generally sudden. The etiology is usually multifactorial, occurring as a consequence of direct inhibitory effects of inflammatory cytokines, erythropoietin deficiency, blunted erythropoietic response ...
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The legacy of a critical illness

British Journal of Hospital Medicine, 2007
Improved management of the acute phase of a critical illness ensures that approximately two in three patients will eventually leave hospital, yet survival does not necessarily mean a return to full health. The more widespread use of follow-up clinics in patients discharged from an intensive care unit (ICU) has shown a substantial legacy in terms of ...
Kannika, Sukantarat, Robin, Williamson
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Critical illness polyneuromyopathy

American Journal of Health-System Pharmacy, 2012
The clinical characteristics of and treatment approaches for critical illness polyneuromyopathy (CIPNM) are reviewed.CIPNM is an acute axonal sensory-motor polyneuropathy that tends to occur after the development of respiratory insufficiency in patients with systemic inflammatory response syndrome, sepsis, or multiple-organ dysfunction syndrome ...
Jennifer, Confer   +2 more
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The Gut in Critical Illness

Current Gastroenterology Reports
The purpose of this narrative review is to describe the mechanisms for gut dysfunction during critical illness, outline hypotheses of gut-derived inflammation, and identify nutrition and non-nutritional therapies that have direct and indirect effects on preserving both epithelial barrier function and gut microbiota during critical illness.Clinical and ...
Jayshil J, Patel, Mark, Barash
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Sex and critical illness

Current Opinion in Critical Care, 2009
The article reviews and speculates on potential mechanisms underlying sex-related differences in admission patterns, care delivery and outcome of critical illness.Evidence from many countries suggests men are more commonly admitted to intensive care units than are women, and may be more likely to receive aggressive life support.
Robert A, Fowler   +5 more
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Critically ill-Polyneuropathie

Fortschritte der Neurologie ยท Psychiatrie, 1997
"Critically ill" polyneuropathy occurs in patients with artificial respiration. It is more frequent in men than in women. The most frequent underlying diseases, in the course of which CIP was found, were pneumonias, traumas and major surgery. In most cases sepsis and/or multiple organ dysfunction syndrome can be observed.
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Chronic Critical Illness

New England Journal of Medicine, 2014
Early in my intern year, I admitted an 80-year-old man with pneumonia to the intensive care unit (ICU). He had hypotension and was struggling to breathe, and my senior resident and I told his family that it was touch and go. Their response: Do everything. He had repaired cars for a living, and he was a tough guy, a fighter.
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Dyslipidemia in the Critically Ill

Critical Care Clinics, 2006
Total and HDL cholesterol levels fall at the onset of acute illness and the cholesterol levels normalize as the patient recovers. Hypocholesterolemia may predispose the critically ill patient to sepsis and adrenal failure. Early enteral nutrition and tight glycemic control accelerate the recovery of the cholesterol levels.
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