Results 61 to 70 of about 1,566,243 (295)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Determinants of Critical Infrastructure Resources

open access: yesFoundations of Management, 2017
This article is devoted to the issue of how resources are interpreted in the form of technology reactors that, as a result of unexpected circumstances, turn into pyramidal or avalanche threat dynamics.
Ostrowska Teresa, Krupa Tadeusz
doaj   +1 more source

Identifying critical elements of road infrastructure using cascading impact assessment

open access: yesTransport, 2020
Road transport is a key means of transporting people and cargo on land. Its particular advantages are speed and operability, which are balanced, however, by dependence on road infrastructure.
David Rehak   +3 more
doaj   +1 more source

Critical Infrastructure Safety Management [PDF]

open access: yesTransactions on Transport Sciences, 2009
Critical infrastructure is a set of mutually interconnected networks, i.e., the systems of various sectors of a human system. An interconnection of systems means their mutual dependence. Therefore, in connection with safe critical infrastructure and with sustainable development potential, it is necessary to solve several problems, namely the safety of ...
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The terrorist threat to critical infrastructure from the perspective of criminal risk

open access: yesBulletin of "Carol I" National Defense University
The field of critical infrastructure protection emerged as part of the fight against terrorism. Although a transition to an all-hazards approach has taken place, terrorism remains a significant threat to entities providing essential services. The relief
Sorina-Denisa POTCOVARU
doaj   +1 more source

3D sensors in critical infrastructure

open access: yesMATEC Web of Conferences, 2018
The danger of terrorism is a result of the increased risk of critical infrastructure. We will focus on enumerating each area then listing of possible real uses in security and protection and finally we will focus in the list of used 3D sensors (in ...
Miroslav Marcanik   +2 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Elektroenergetyczna infrastruktura krytyczna w województwie zachodniopomorskim – 10 lat po blackoucie

open access: yesPrzegląd Zachodniopomorski, 2020
Electricity grids failures, caused by the natural forces, occur often locally and can be handled by the grid’s operator services. If, however, a large number of elements are damaged over a vast area, a large territory is devoid of power supply.
Ewelina Kochanek
doaj   +1 more source

Home - About - Disclaimer - Privacy