Results 91 to 100 of about 107,923 (299)
Advanced Science, EarlyView.This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du +15 more
wiley +1 more source
Majalah Kedokteran Bandung, 2020 In 2014, The Society for Vascular Surgery revealed a new classification system for Critical Limb Ischemia (CLI) referred as the Society for Vascular Surgery Lower Extremity Threatened Limb Classification System based on Wound, Ischemia, and foot ...
Teguh Marfen Djajakusumah +3 more
doaj +1 more source
AGING MEDICINE, EarlyView.Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang +11 more
wiley +1 more source
JCI Insight, 2018 The most severe manifestation of peripheral arterial disease (PAD) is critical limb ischemia (CLI). CLI patients suffer high rates of amputation and mortality; accordingly, there remains a clear need both to better understand CLI and to develop more ...
Terence E. Ryan +15 more
semanticscholar +1 more source
The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity
AGING MEDICINE, EarlyView.Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley +1 more source
Annals of Vascular Surgery - Brief Reports and InnovationsWe report a case of a patient that developed acute limb ischemia secondary to atherectomy related embolization that was rescued with a deep venous arterialization (DVA) procedure.
Alejandra P. Rodriguez +5 more
doaj +1 more source
Cell Transplantation, 2019 We first compared long-term clinical outcomes in treating critical limb ischemia (CLI) and foot ulcer in patients with diabetes between autologous bone marrow mesenchymal stem cell (BMMSC) and bone-marrow-derived mononuclear cell (BMMNC) transplants ...
De-bin Lu +11 more
semanticscholar +1 more source
Annals of Gastroenterological Surgery, EarlyView.Implementation of a multimodal perioperative care program and reduction of postoperative complications. ABSTRACT Purpose This retrospective study aimed to assess the clinical effectiveness of a multimodal perioperative care program in reducing postoperative complications in elderly patients undergoing gastrectomy for gastric cancer.
Keiichi Fujiya +13 more
wiley +1 more source
Myocardial revascularization in diabetic patients presenting with critical limbischemia
Сахарный диабет, 2010 The frequency of diabetic complications remains high despite the development of improved therapeutic modalities. Macroangiopathy continues to bethe predominant complication while coronary heart disease is the main cause of mortality.This paper considers ...
Ivan Ivanovich Dedov +2 more
doaj +1 more source
Circulation. Cardiovascular Interventions, 2019 BACKGROUND The aim of this study was to develop a predictive model for mortality risk based on preoperative risk factors, including the Wound, Ischemia, Foot Infection (WIfI) classification, in patients undergoing revascularization for critical limb ...
N. Azuma +8 more
semanticscholar +1 more source