Results 81 to 90 of about 39,076 (258)
The Diagnostic Classification of Critical Limb Ischemia
Annals of Vascular Diseases, 2018 With the global epidemic of diabetes, diagnosis of critical limb ischemia (CLI) has become very complex due to mixture of microangiopathy, infection and sometimes neuropathy with the pure ischemia. We still sometimes encounter the patients with extensive tissue loss due to misdiagnosis of ischemia or infection in previous hospital.
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BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Distal transradial access (dTRA) has gained attention for its lower risk of vascular complications compared to conventional transradial access (TRA). However, its feasibility and safety in patients with out‐of‐hospital cardiac arrest (OHCA) undergoing emergency percutaneous coronary intervention (PCI) remain uncertain.
Shiori Kawakami +9 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Intravascular ultrasound (IVUS) may be beneficial for guiding endovascular revascularization in patients with chronic limb‐threatening ischemia (CLTI); however, its use remains limited. Methods We surveyed interventional radiologists, vascular surgeons, and interventional cardiologists in the United States, Canada, and the United ...
Marc‐André d'Entremont +15 more
wiley +1 more source
Functional outcome of critical limb ischemia [PDF]
Journal of Vascular Surgery, 2007 Results of treatment for critical limb ischemia have traditionally focused on physician-oriented end points related to limb salvage surgery. Although numerous studies have demonstrated excellent patency and limb salvage after surgical revascularization procedures, survival in this patient population is poor, comorbidities reducing quality of life are ...
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Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Percutaneous femoral access serves as the cornerstone of endovascular therapy of lower extremity arterial disease. In complex cases, the arterial disease of lower extremity are involve in ipsilateral iliac artery pathology, which conventional treatment strategies typically require multiple punctures or staged procedures.
Guangfeng Zheng +6 more
wiley +1 more source
TIE2‐expressing monocytes/macrophages regulate revascularization of the ischemic limb
EMBO Molecular Medicine, 2013 A third of patients with critical limb ischemia (CLI) will eventually require limb amputation. Therapeutic neovascularization using unselected mononuclear cells to salvage ischemic limbs has produced modest results.
Ashish S. Patel +17 more
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Epilepsia, EarlyView.Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli +43 more
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Epilepsia Open, EarlyView.Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
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