Results 71 to 80 of about 39,076 (258)

Cell Therapy in Patients with Critical Limb Ischemia

Stem Cells International, 2015
Critical limb ischemia (CLI) represents the most advanced stage of peripheral arterial obstructive disease (PAOD) with a severe obstruction of the arteries which markedly reduces blood flow to the extremities and has progressed to the point of severe ...
Rita Compagna, Bruno Amato, Salvatore Massa, Maurizio Amato, Raffaele Grande, Lucia Butrico, Stefano de Franciscis, Raffaele Serra   +7 more
doaj   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Critical limb ischemia: an update for interventional radiologists

Diagnostic and Interventional Radiology, 2013
Critical limb ischemia (CLI) is a growing epidemic with bleak patient outcomes. A variety of treatment modalities have been adopted to address CLI based on comorbidities, life expectancy, and the nature of the arterial disease.
Nicholas F. Brazeau,, Erique G. Pinto,, Harlan B. Harvey,, George R. Oliveira,, Benjamin J. Pomerantz,, Stephan Wicky,, Rahmi Oklu   +6 more
doaj   +1 more source

Critical limb ischemia.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 1996
Chronic critical limb ischemia is defined as ischemia which generally endangers the distal part of a limb. If the ischemia is unrelenting, there is a high risk that amputation will be required. These critical limbs were amputated as an initial treatment long ago.
openaire   +2 more sources

Identification of senescence‐related genes in Parkinson's disease reveals candidate therapeutic targets and pathological processes

Animal Models and Experimental Medicine, EarlyView.
At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu, Tingting Liu, Xiangshu Cheng, Jianshe Wei   +3 more
wiley   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Single‐Stage Anatomic Reconstruction of Anterior Cruciate Ligament, Posterior Cruciate Ligament, Medial Collateral Ligament, and Posterolateral Corner for Multiligament Knee Injury

Arthroscopy Techniques, EarlyView.
Abstract Multiligament knee injuries represent rare and challenging injuries that require complex surgical management to restore stability and function. Current evidence supports anatomic single‐stage reconstructions when feasible in order to re‐establish knee kinematics and enable early rehabilitation.
Logan D. Moews, Joseph C. Brinkman, Felipe Casanova, Napatpong Thamrongskulsiri, Jacob T. Morgan, Tomas F. Vega, Jorge Chahla   +6 more
wiley   +1 more source

Deep venous arterialization in the acute setting for embolic complication after endovascular procedure

Annals of Vascular Surgery - Brief Reports and Innovations
We report a case of a patient that developed acute limb ischemia secondary to atherectomy related embolization that was rescued with a deep venous arterialization (DVA) procedure.
Alejandra P. Rodriguez, Antonio Solano, Sofia K. Babool, Suyue M. Zhang, Lawrence A. Lavery, Michael C. Siah   +5 more
doaj   +1 more source

Supine‐Position Shoulder Arthroscopy Using the Anterior Portal as the Initial Approach

Arthroscopy Techniques, EarlyView.
Abstract Traditional shoulder arthroscopy mostly adopts the beach chair position or lateral decubitus position. Beach chair position is associated with the risk of cerebral hypoperfusion due to the vertical distance between the carotid artery and the heart, whereas lateral decubitus may induce brachial plexus palsy caused by excessive traction.
Weidong Wang, Yingbiao Wang, Sen Li, Mu Gao   +3 more
wiley   +1 more source

Myocardial revascularization in diabetic patients presenting with critical limbischemia

Сахарный диабет, 2010
The frequency of diabetic complications remains high despite the development of improved therapeutic modalities. Macroangiopathy continues to bethe predominant complication while coronary heart disease is the main cause of mortality.This paper considers ...
Ivan Ivanovich Dedov, Victor Yur'evich Kalashnikov, Konstantin Vladimirovich Melkozerov   +2 more
doaj   +1 more source