Results 11 to 20 of about 5,041,885 (292)
, 2017 Patients with CLI have a poor prognosis, the estimated 3-year probability of mortality being 35.1%. As a result, preference to less burdensome endovascular treatment should be given, provided the same levels of symptomatic improvement can be achieved as with open surgery.
Suparna Rao +2 more
core +4 more sources
JACC: Basic to Translational Science, 2023 Summary: Hypoxia-induced endothelial cell death and impaired angiogenesis are the main pathophysiological features of critical limb ischemia. Mechanistically, proprotein convertase subtilisin/kexin type 9 (PCSK9) promoted Smac translocation from ...
Meixin Zhang, MM +9 more
doaj +2 more sources
Cardiology Clinics, 2015 Critical limb ischemia (CLI), the most advanced form of peripheral artery disease (PAD), carries grave implications with regard to morbidity and mortality. Within 1 year of CLI diagnosis, 40% to 50% of diabetics will experience an amputation, and 20% to 25% will die. Management is optimally directed at increasing blood flow to the affected extremity to
Sarah, Elsayed, Leonardo C, Clavijo
openaire +3 more sources
Cells, 2023 Background: Critical limb ischemia represents an advanced stage of peripheral arterial disease. Angioplasty improves blood flow to the limb; however, some patients progress irreversibly to lower limb amputation.
Daniel Santillán-Cortez +15 more
doaj +2 more sources
Critical limb ischemia: an update for interventional radiologists [PDF]
Diagnostic and Interventional Radiology, 2013 Critical limb ischemia (CLI) is a growing epidemic with bleak patient outcomes. A variety of treatment modalities have been adopted to address CLI based on comorbidities, life expectancy, and the nature of the arterial disease.
Nicholas F. Brazeau, +6 more
doaj +2 more sources
Critical limb ischemia: current challenges and future prospects
Vascular Health and Risk Management, 2018 Luigi Uccioli,1 Marco Meloni,1 Valentina Izzo,1 Laura Giurato,1 Stefano Merolla,2 Roberto Gandini2 1Department of Systems Medicine, 2Department of Interventional Radiology, Università di Tor Vergata Roma, Rome, Italy Abstract: Critical limb ...
Uccioli L +5 more
doaj +2 more sources
Current Treatment Options in Cardiovascular Medicine, 2010 Critical limb ischemia (CLI), defined as chronic ischemic rest pain, ulcers, or gangrene attributable to objectively proven arterial occlusive disease, is the most advanced form of peripheral arterial disease. Traditionally, open surgical bypass was the only effective treatment strategy for limb revascularization in this patient population.
Schanzer, Andres, Conte, Michael S.
openaire +7 more sources
Modern multidisciplinary team approach is crucial in treatment for critical limb threatening ischemia. [PDF]
, 2021 The aim of this study was to provide a brief overview of the history the multidisciplinary team approach, highlighting the benefit to the patient with critical limb threatening ischemia in relation to health care economics.
Driver, Vickie R +26 more
core +1 more source
Chronic Critical Limb Ischemia [PDF]
Deutsches Ärzteblatt international, 2012 Some 40 000 lower limb amputations are performed in Germany each year, 70% of them in diabetics. About 80% of all major amputations may be preventable with the use of new interventional and vascular surgical procedures, particularly on the arteries of the leg and foot. We present the current state of the art in revascularization techniques and evaluate
Dohmen, Arndt +4 more
openaire +3 more sources
Limb salvage following below-the-ankle angioplasty in critical limb ischemia
Indian Journal of Vascular and Endovascular Surgery, 2020 Aim: The aim was to report limb salvage following below-the-ankle (BTA) angioplasty as an adjunct to proximal angioplasty in patients with critical limb ischemia (CLI).
B Nishan +4 more
doaj +1 more source