Results 61 to 70 of about 674,738 (298)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Synergic process of molybdenum recovery and ceramic preparation for clean and efficient utilization of industrial leaching residues

Cleaner Engineering and Technology
Ammonia-leaching residues of roasted molybdenite concentrates are intractable wastes and are mostly stockpiled in factories. Common treatments suffer from low Mo recovery and secondary pollution. This study has developed a synergistic process involving a
Guihong Han, Yanghao Feng, Mengyu You, Hu Sun, Shengpeng Su, Bingbing Liu, Yanfang Huang   +6 more
doaj   +1 more source

Determination of 42 Trace Elements in Silicate Glass Reference Materials by High Spatial Resolution LA-ICP-MS

Yankuang ceshi, 2023
BACKGROUNDCritical metal elements are a group of metal elements including rare metal elements (e.g., Li, Be, Rb, Cs, Nb, Ta, Zr, Hf, W), rare earth elements (REEs), rare disperse elements (e.g., Ga, Ge, Se, Cd, In, Te, Re, Tl) and rare precious elements (
Tao HE, Chenxi ZHANG, Wen ZHANG, Yantong FENG, Ting LIANG, Xiaoyun QIU, Hui CAO, Zhaochu HU   +7 more
doaj   +1 more source

Unconventional Quantum Criticality due to Critical Valence Transition

, 2014
Quantum criticality due to the valence transition in some Yb-based heavy fermion metals has gradually turned out to play a crucial role to understand the non-Fermi liquid properties that cannot be understood from the conventional quantum criticality ...
Miyake, Kazumasa, Watanabe, Shinji
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Critical loads for lead in France: First results on forest soils [PDF]

, 2003
Within the framework of the United Nation Convention on Long Range Transboundary Air Pollution, France is part of the Working Group on Effect which aims at evaluating the impact of atmospheric deposition on ecosystems by calculating critical loads.
Goddéris, Yves, Hernandez, Laura, Moncoulon, David, Party, Jean-Paul, Probst, Anne   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A novel molybdenite depressant for efficient selective flotation separation of chalcopyrite and molybdenite

International Journal of Mining Science and Technology
A novel small molecule depressant (M-DEP) was used to separate chalcopyrite and molybdenite via flotation. The results showed that M-DEP had an excellent selective depression on molybdenite, while had little effect on the flotation of chalcopyrite.
Mengyao Qi, Weijun Peng, Wei Wang, Yijun Cao, Longyu Zhang, Yukun Huang   +5 more
doaj   +1 more source

Introduction to a Resources Special Issue on Criticality of the Rare Earth Elements: Current and Future Sources and Recycling

, 2018
The rare earth elements (REE) are vital to modern technologies and society and are amongst the most important of the critical elements. This special issue of Resources examines a number of facets of these critical elements, current and future sources of ...
Jowitt, Simon M.
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source