GraphVAMPnet, a graph neural network–based deep learning framework, successfully overcomes the permutation challenge in analyzing molecular dynamics trajectories of self‐assembly of PtB complexes. It accurately identifies three slow collective variables and reveals two competing kinetic pathways—incremental and hopping growth—governing Pt(II ...
Zige Liu +3 more
wiley +1 more source
Development and Characterization of EGCG-Loaded TPGS/Poloxamer 407 Micelles with Evaluation of In Vitro Drug Release and In Vivo Pharmacokinetics and Tolerability Observations Following Oral Administration. [PDF]
Wong CN +6 more
europepmc +1 more source
Comparative Stability of Synthetic and Natural Polymeric Micelles in Physiological Environments: Implications for Drug Delivery. [PDF]
Polat H +4 more
europepmc +1 more source
Hydrothermal synthesis records for rare‐earth compounds are repurposed to learn mineralization rules. An extreme gradient boosting model ingests precursors, additives, and engineered descriptors to predict product phases, crystallization temperature, and pH. Feature importance indicates dominant thermodynamic control with kinetic modulation, suggesting
Juejing Liu +6 more
wiley +1 more source
From Conventional to Next-Generation Strategies: Recent Advances in Polymeric Micelle Preparation for Drug Delivery. [PDF]
Cho S +3 more
europepmc +1 more source
Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane +1 more
wiley +1 more source
The surface and micellar properties of ethanolamine based surface active ionic liquids in the presence of drug aspirin. [PDF]
Janbezar E +3 more
europepmc +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
Emergent Chemical Reactivity and Complexity of RNA Condensates
RNA condensates capable of substrate enrichment and catalysis modulate their environment. Could this start a catalytic selection loop or evolution? Abstract The RNA world hypothesis posits the existence of life‐like assemblies that consisted mostly of RNA.
Samuel Hauf +4 more
wiley +2 more sources

