Results 211 to 220 of about 60,314 (313)

Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere   +4 more
wiley   +1 more source

Nanoparticles Functionalized with Polymer Brushes for Gene Delivery

open access: yesAdvanced NanoBiomed Research, EarlyView.
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley   +1 more source

Water‐Soluble Molecular Wires for Membrane Potential Imaging

open access: yesAngewandte Chemie, EarlyView.
Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib   +9 more
wiley   +2 more sources

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman   +2 more
wiley   +1 more source

A Fluorogenic Hydrazino‐Pictet–Spengler Reaction in Live Cells

open access: yesAngewandte Chemie, EarlyView.
A fluorogenic hydrazino‐Pictet–Spengler (HIPS) ligation reaction is used to label lipid‐derived aldehydes under wash‐free conditions in live cells. This innovative technique enables wash‐free imaging within biological systems, offering invaluable insights into the extent and localization of oxidative stress.
Kaleena Basran, Nathan W. Luedtke
wiley   +2 more sources

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai   +5 more
wiley   +1 more source

Size‐Selective Functionalization of Sugars and Polyols Using Zeolites for Renewable Surfactant Production

open access: yesAngewandte Chemie, EarlyView.
A zeolite‐catalyzed strategy enables size‐selective monoacetalization of sugars and polyols in a single step by leveraging pore confinement to distinguish between mono‐ and multi‐substituted species. This broadly applicable method avoids protection steps and excess reagents, opening new routes to bio‐based amphiphiles with strong surface activity and ...
Songlan Sun   +10 more
wiley   +2 more sources

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