Results 261 to 270 of about 60,314 (313)

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Porous hierarchically ordered hydrogels demonstrating structurally dependent mechanical properties. [PDF]

Nat Commun
Lloyd EC, Dhakal S, Amini S, Alhasan R, Fratzl P, Tree DR, Morozova S, Hickey RJ.   +7 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Optimizing Rhamnolipid Performance by Modulating the Expression of Fatty Acid Synthesis Genes <i>fabA</i> and <i>fabZ</i> in <i>Pseudomonas aeruginosa</i> PAO1. [PDF]

Genes (Basel)
Lu J, Chen Z, Zhu H, Tang Q, Yang Z.
europepmc   +1 more source

Single‐component cationic polyethylenimine thermogel for sustained and localized gene delivery to combat multi‐drug resistant cancer

BMEMat, EarlyView.
A cationic thermogelling copolymer employing branched PEI‐25 kDa as the sole hydrophilic segment can be facilely complexed with plasmid by physical mixing in the sol phase. Spontaneous gelation is achieved via self‐assembly after injection due to physiological temperature. Sustained and localized release of plasmid from the cationic PEI‐thermogel leads
Qianyu Lin, Minting Liu, Lingjie Ke, Nicholas Wei Xun Ong, Joey Hui Min Wong, Cally Owh, Valerie Ow, Belynn Sim, Yi Jian Boo, Jason Y. C. Lim, Yunlong Wu, Xian Jun Loh   +11 more
wiley   +1 more source

Layer-by-Layer Coated Alginate Hydrogels with Antibacterial Activity Based on Bacteriophage and Curcumin Combination. [PDF]

ACS Omega
Guren A, Yucefaydali A, Gundogdu D, Bozkurt A, Butun V, Soyer Y, Erel-Goktepe I.   +6 more
europepmc   +1 more source

Study of Polyethylene Oxide-<i>b</i>-Poly(<i>ε</i>-caprolactone-<i>ran</i>-<i>δ</i>-valerolactone) Amphiphilic Architectures and Their Effects on Self-Assembly as a Drug Carrier. [PDF]

Polymers (Basel)
Wang C, Wu T, Li Y, Liu J, Wang Y, Wang K, Li Y, Leng X.   +7 more
europepmc   +1 more source

Cryo-EM for atomic characterization of supramolecular gels.

Faraday Discuss
Sonani RR, Bianco S, Kreutzberger MAB, Adams DJ, Egelman EH.   +4 more
europepmc   +1 more source