Results 151 to 160 of about 457,166 (295)

LLM-supported collaborative ontology design for data and knowledge management platforms. [PDF]

Front Big Data
Kampars J, Mosans G, Jogi T, Roters F, Vajragupta N.   +4 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Integrating text mining and knowledge graph to enhance biopharmaceutical process optimization. [PDF]

PLoS One
Bhowmik S, Anandakrishnan M, Klein L, Arighi C, Gioioso M, Wu C, Brockmeier A, Vijay-Shanker K, Chen C.   +8 more
europepmc   +1 more source

Cybersecurity Ontology for Critical Infrastructures

Proceedings of the 9th International Joint Conference on Knowledge Discovery, Knowledge Engineering and Knowledge Management, 2017
Ulrike Lechner, Sandra Bergner
openaire   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Optimizing large language models for ontology-based annotation: a study on gene ontology in biomedical texts. [PDF]

BioData Min
Devkota P, Mohanty SD, Manda P.
europepmc   +1 more source

Rethinking constitutional ontology

Revus
Karl Loewenstein devised an ontological classification of constitutions based on his study of constitutional enactment and operation. His typology, which became particularly known in Europe and Latin America, offers valuable insights into the complex interplay between political power and constitutional norms.
openaire   +2 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

AUTOENCODIX: a generalized and versatile framework to train and evaluate autoencoders for biological representation learning and beyond. [PDF]

Nat Comput Sci
Joas MJ, Jurenaite N, Praščević D, Scherf N, Ewald J.   +4 more
europepmc   +1 more source

Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields

Advanced Science, EarlyView.
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang, Wenchao Du, Kees Jan van Groenigen, Josep Peñuelas, Scott X. Chang, Lian Song, Chuang Cai, Yu Wang, Lin Deng, Zhengkun Hu, Weishou Shen, Qicong Wu, Haiyang Yu, Ying Yin, Fuxun Ai, Wei Zhou, Dongming Wang, Jianqiang Sun, Xiaoyuan Yan, Renfang Shen, Jiabao Zhang, Hongyan Guo, Chunwu Zhu   +22 more
wiley   +1 more source