Results 191 to 200 of about 457,166 (295)

Digital Biomarkers of Cytokine Release Syndrome: Scoping Review and Ontology Development of the Role and Relevance of Digital Measures Using a Mixed Methods Approach.

J Med Internet Res
Medberry CJ, Angel CZ, Batavia AS, Bradley S, Camerlingo N, Chen M, Datoo M, Kamdar P, Koenig E, Kusters L, Marquez C, Nukala U, Pettinati M, Phillips R, Sanchez DP, Shafagati N, Siegelman J, Stewart M, Varga C, Vandendriessche B, Wilkes M, Wolff-Hughes DL, Zahavi D, Zorman S, McClenahan SJ.   +24 more
europepmc   +1 more source

Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals. [PDF]

Elife
Stewart C, Liddle TA, Tolla E, Lewis JE, Marshall C, Evans NP, Morgan PJ, Ebling FJP, Stevenson TJ.   +8 more
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Ontologies as the semantic bridge between artificial intelligence and healthcare. [PDF]

Front Digit Health
Ambalavanan R, Snead RS, Marczika J, Towett G, Malioukis A, Mbogori-Kairichi M.   +5 more
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Top-Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains. [PDF]

J Mass Spectrom
Askarani MF, Poulos W, Dashtaki MR, Sadeghi SA, Cibelli JB, Fang F, Sun L.   +6 more
europepmc   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Whole transcriptome analysis reveals T cell signaling activation in septic patients with thrombocytopenia. [PDF]

Sci Rep
Chen IC, Jiang YH, Hsiao TH, Chao WC.
europepmc   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Genes associated with epithelial mesenchymal transition (EMT) in cervical cancer progression. [PDF]

Discov Oncol
Kumari K, Gupta RK, Kumar S, Prasad SB.
europepmc   +1 more source