Transcriptomic analysis of field-droughted sorghum from seedling to maturity reveals biotic and metabolic responses. [PDF]
, 2019 Drought is the most important environmental stress limiting crop yields. The C4 cereal sorghum [Sorghum bicolor (L.) Moench] is a critical food, forage, and emerging bioenergy crop that is notably drought-tolerant.
Baker, Christopher R +27 more
core +3 more sources
Modelling and analysis of biochemical signalling pathway cross-talk [PDF]
, 2010 Signalling pathways are abstractions that help life scientists structure the coordination of cellular activity. Cross-talk between pathways accounts for many of the complex behaviours exhibited by signalling pathways and is often critical in producing ...
Emanuela Merelli +3 more
core +5 more sources
Dynamics of Nucleation in the Ising Model [PDF]
, 1994 Reactive pathways to nucleation in a three-dimensional Ising model at 60% of the critical temperature are studied using transition path sampling of single spin flip Monte Carlo dynamics.
Caruncho, H. J. +6 more
core +2 more sources
Pathways into multiple exclusion homelessness in seven UK cities [PDF]
, 2012 This paper interrogates pathways into multiple exclusion homelessness (MEH) in the UK and, informed by a critical realist theoretical framework, explores the potential causal processes underlying these pathways.
Bramley, Glen +2 more
core +1 more source
Making the most of community energies:Three perspectives on grassroots innovation [PDF]
, 2016 Grassroots innovations for sustainability are attracting increasing policy attention. Drawing upon a wide range of empirical research into community energy in the UK, and taking recent support from national government as a case study, we apply three ...
Abramsky K +13 more
core +1 more source
“What if There's Something Wrong with Her?”‐How Biomedical Technologies Contribute to Epistemic Injustice in Healthcare [PDF]
, 2020 While there is a steadily growing literature on epistemic injustice in healthcare, there are few discussions of the role that biomedical technologies play in harming patients in their capacity as knowers.
Alexander Michelle +33 more
core +1 more source
Assembling defenses against therapy-resistant leukemic stem cells: Bcl6 joins the ranks [PDF]
, 2011 The resistance of leukemic stem cells in response to targeted therapies such as tyrosine kinase inhibitors (TKIs) relies on the cooperative activity of multiple signaling pathways and molecules, including TGFβ, AKT, and FOXO transcription factors ...
Austin +30 more
core +2 more sources
Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]
, 2015 TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Bellamy, Christopher O +4 more
core +1 more source
An evaluation of DNA-damage response and cell-cycle pathways for breast cancer classification [PDF]
, 2014 Accurate subtyping or classification of breast cancer is important for ensuring proper treatment of patients and also for understanding the molecular mechanisms driving this disease.
Fard, Atefeh Taherian +2 more
core +5 more sources
Early Screening and Standardized Management Pathway for Bronchial Asthma in Shenzhen Community Healthcare Settings (Trial Version) [PDF]
Zhongguo quanke yixue, 2023 Early screening, standardized diagnosis and treatment as well as effective management are keys to improve the control level and quality of life in patients with bronchial asthma (BA) , a common chronic airway disease.
Shenzhen Group of Integrated Medical and Preventive Medicine Program for Respiratory Diseases, Shenzhen Center for the Prevention and Treatment of Major Respiratory Diseases, Shenzhen Community Health Association
doaj +1 more source