Results 21 to 30 of about 9,005,815 (383)
Cognitive behavioral therapy for insomnia (CBT ⁃ I) boasts convincing evidence from randomized controlled clinical trials, yet its practical application encounters substantial barriers.
ZHANG Peng, CHEN Tao, XU Li
doaj +1 more source
Implementing a Sepsis Resuscitation Bundle Improved Clinical Outcome: A Before-and-After Study [PDF]
BACKGROUND: Unlike other diseases, the management of sepsis has not been fully integrated in our daily practice. The aim of this study was to determine whether repeated training could improve compliance with a 6-h resuscitation bundle in patients with ...
Jeongmin Kim+3 more
doaj +1 more source
Autophagy and autophagy-related pathways in cancer
Maintenance of protein homeostasis and organelle integrity and function is critical for cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates the delivery of various cellular cargoes to lysosomes for degradation and ...
Jayanta Debnath, Noor Gammoh, K. Ryan
semanticscholar +1 more source
Nrf2 Activator PB125® as a Potential Therapeutic Agent against COVID-19
Nrf2 is a transcription factor that regulates cellular redox balance and the expression of a wide array of genes involved in immunity and inflammation, including antiviral actions.
Joe M. McCord+4 more
doaj +1 more source
Next‐level multiomics helps define new critical pathways in developmental hematopoiesis [PDF]
David G. Kent
doaj +2 more sources
Targeting p53 pathways: mechanisms, structures and advances in therapy
The TP53 tumor suppressor is the most frequently altered gene in human cancers, and has been a major focus of oncology research. The p53 protein is a transcription factor that can activate the expression of multiple target genes and plays critical roles ...
Haolan Wang+3 more
semanticscholar +1 more source
Care Pathway for Cancer Survivorship in Korea: Trend of Breast Cancer Pathway from 2003 to 2010 [PDF]
ObjectivesThe survival rate of cancer patients has exceeded 60%. Although cancer survivors may die of other diseases except cancer, the health management system including chronic disease prevention-management for cancer survivors, has not been ...
Hwa Jeong Seo, Dong Yong Noh
doaj +1 more source
Conformance Analysis of Clinical Pathway Using Electronic Health Record Data [PDF]
ObjectivesThe objective of this study was to confirm the conformance rate of the actual usage of the clinical pathway (CP) using Electronic Health Record (EHR) log data in a tertiary general university hospital to improve the CP by reflecting real-world ...
Sooyoung Yoo+7 more
doaj +1 more source
Hypertension (arterial blood pressure ≥ 140/90 mmHg) is a risk factor for cardiovascular diseases, with the greatest burden of attributable deaths in Chile, having a national prevalence of 27.6%.
Francisca Barake+5 more
doaj +1 more source
Background: Relapsing–remitting multiple sclerosis (RRMS) is a subtype of degenerative inflammatory demyelinating disease of multifactorial origin that affects the central nervous system and leads to multifocal neurological impairment.Objectives: To ...
César Caparó-Zamalloa+17 more
doaj +1 more source