Results 41 to 50 of about 7,053,549 (295)

Neural Response Interpretation through the Lens of Critical Pathways [PDF]

, 2021
Is critical input information encoded in specific sparse pathways within the neural network? In this work, we discuss the problem of identifying these critical pathways and subsequently leverage them for interpreting the network's response to an input ...
Kim, St, Saurabh Khanduja, Khakzar, A, Khanduja, S, Ashkan Khakzar, Seong Tae Kim, Baselizadeh, S, Nassir Navab, Soroosh Baselizadeh, Christian Rupprecht, Rupprecht, C, Navab, N   +11 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The development, implementation and evaluation of clinical pathways for chronic obstructive pulmonary disease (COPD) in Saskatchewan: protocol for an interrupted times series evaluation

BMC Health Services Research, 2017
Background Chronic obstructive pulmonary disease (COPD) has substantial economic and human costs; it is expected to be the third leading cause of death worldwide by 2030. To minimize these costs high quality guidelines have been developed.
Thomas Rotter, Christopher Plishka, Mohammed Rashaad Hansia, Donna Goodridge, Erika Penz, Leigh Kinsman, Adegboyega Lawal, Sheryl O’Quinn, Nancy Buchan, Patricia Comfort, Prakesh Patel, Sheila Anderson, Tanya Winkel, Rae Lynn Lang, Darcy D. Marciniuk   +14 more
doaj   +1 more source

Evaluation of a critical pathway for stroke

Journal of Osteopathic Medicine, 1997
Abstract The diagnosis of stroke, which is diagnosis-related group (DRG) 014, is the fourth most frequent discharge DRG at Macomb Hospital Center, Warren, Michigan. The length of stay for stroke was 7.52 days before intervention. Quality improvement techniques identified areas of delay that presented opportunities for improvement.
G, Ross, D, Johnson, M, Kobernick
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Critical molecular pathways in CLL therapy

Molecular Medicine, 2018
Chronic lymphocytic leukemia (CLL), the most frequent type of leukemia in western countries, is characterized by the progressive accumulation in blood, bone marrow and lymphoid tissues of monoclonal B lymphocytes with a characteristic immunophenotype ...
Gerardo Ferrer, Emili Montserrat
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Avaliação não invasiva de pacientes submetidos à intervenção percutânea no infarto do miocárdio Noninvasive assessment of patients undergoing percutaneous intervention in myocardial infarction

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: A reestenose pós-intervenção coronariana percutânea primária permanece um problema de relevância clínica, mesmo com o implante de stents.
Rica Dodo Delmar Buchler, Expedito E. Ribeiro, Antonio de Padua Mansur, Paola Smanio, Romeu Sergio Meneghelo, William Azem Chalela, Carlos Alberto Buchpiguel, Jorge Roberto Buchler, Eric R. Bates, Eulogio E. Martinez   +9 more
doaj  

Assessing the reproducibility, stability, and biological interpretability of multimodal computed tomography image features for prognosis in advanced non‐small cell lung cancer

iRADIOLOGY
Background Despite the existence of proposed prognostic features on computed tomography (CT) for patients with advanced‐stage non‐small cell lung cancer (NSCLC), including radiologists' handcrafted (RaH) features, radiomics features, and deep learning ...
Jiajun Wang, Gang Dai, Xiufang Ren, Ruichuan Shi, Ruibang Luo, Jianhua Liu, Kexue Deng, Jiangdian Song   +7 more
doaj   +1 more source