Results 41 to 50 of about 6,548,421 (205)

Critical molecular pathways in CLL therapy

Molecular Medicine, 2018
Chronic lymphocytic leukemia (CLL), the most frequent type of leukemia in western countries, is characterized by the progressive accumulation in blood, bone marrow and lymphoid tissues of monoclonal B lymphocytes with a characteristic immunophenotype ...
Gerardo Ferrer, Emili Montserrat
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Avaliação não invasiva de pacientes submetidos à intervenção percutânea no infarto do miocárdio Noninvasive assessment of patients undergoing percutaneous intervention in myocardial infarction

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: A reestenose pós-intervenção coronariana percutânea primária permanece um problema de relevância clínica, mesmo com o implante de stents.
Rica Dodo Delmar Buchler, Expedito E. Ribeiro, Antonio de Padua Mansur, Paola Smanio, Romeu Sergio Meneghelo, William Azem Chalela, Carlos Alberto Buchpiguel, Jorge Roberto Buchler, Eric R. Bates, Eulogio E. Martinez   +9 more
doaj  

Assessing the reproducibility, stability, and biological interpretability of multimodal computed tomography image features for prognosis in advanced non‐small cell lung cancer

iRADIOLOGY
Background Despite the existence of proposed prognostic features on computed tomography (CT) for patients with advanced‐stage non‐small cell lung cancer (NSCLC), including radiologists' handcrafted (RaH) features, radiomics features, and deep learning ...
Jiajun Wang, Gang Dai, Xiufang Ren, Ruichuan Shi, Ruibang Luo, Jianhua Liu, Kexue Deng, Jiangdian Song   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Development of Korean Medicine Clinical Pathways for Hip and Hand Degenerative Arthritis

Journal of Acupuncture Research
Background: This study aimed to develop standard clinical pathways (CP) for patients with degenerative hip and hand arthritis, ensuring consistent care, maximizing treatment effectiveness, and enhancing clinical applicability in Korean medicine. Methods:
Seon Changwoo, Kim Min-jeong
doaj   +1 more source

Three pathways for enlarging critical African psychology

, 2020
Departing from the position that critical African psychology is an endeavour whose objective is to harness psychological knowledge in, by, for, and with Africa, as well as the world, but also to critically think Africa into psychology, this article ...
Ratele, K., Cornell, J., Taliep, N., Suffla, S., Malherbe, N.   +4 more
core   +1 more source