Results 61 to 70 of about 1,573,391 (311)
Metabolome alterations in severe critical illness and vitamin D status [PDF]
, 2017 Background Metabolic homeostasis is substantially disrupted in critical illness. Given the pleiotropic effects of vitamin D, we hypothesized that metabolic profiles differ between critically ill patients relative to their vitamin D status.
Dahlin, Amber +27 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Arquivos Brasileiros de Cardiologia, 2010 FUNDAMENTO: A reestenose pós-intervenção coronariana percutânea primária permanece um problema de relevância clínica, mesmo com o implante de stents.
Rica Dodo Delmar Buchler +9 more
doaj
iRADIOLOGYBackground Despite the existence of proposed prognostic features on computed tomography (CT) for patients with advanced‐stage non‐small cell lung cancer (NSCLC), including radiologists' handcrafted (RaH) features, radiomics features, and deep learning ...
Jiajun Wang +7 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Evaluating telemedicine: A focus on patient pathways
, 2006 Evaluations of telemedicine have sought to assess various measures of effectiveness (e.g., diagnostic accuracy), efficiency (e.g., cost), and engagement (e.g., patient satisfaction) to determine its success.
Eatock, J +5 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The influencing pathway of agrivoltaics on soybean protein concentration
Frontiers in Plant ScienceAgrivoltaics has the potential to enable simultaneous energy and food production. However, its impact on crop quality and the underlying mechanisms remain insufficiently understood, which poses a significant challenge to the development of agrivoltaic ...
Yuru Hu +4 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The role of type 4 phosphodiesterases in generating microdomains of cAMP: Large scale stochastic simulations [PDF]
, 2010 Cyclic AMP (cAMP) and its main effector Protein Kinase A (PKA) are critical for several aspects of neuronal function including synaptic plasticity. Specificity of synaptic plasticity requires that cAMP activates PKA in a highly localized manner despite ...
Terrin, A. +35 more
core +1 more source