Results 71 to 80 of about 7,550,631 (352)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

BCS quantum critical phenomena

, 2017
Theoretically, we recently showed that the scaling relation between the transition temperature T_c and the superfluid density at zero temperature n_s (0) might exhibit a parabolic pattern [Scientific Reports 6 (2016) 23863]. It is significantly different
Tao, Yong
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Saturation and Critical Phenomena in DIS [PDF]

, 2009
It is argued that the expected turn-down in $x- Q^2$ of the cross sections (structure functions $F_2(x,Q^2)$), assumed to result from the saturation of parton densities in the nucleon, is related to a phase transition from the (almost) ideal partonic gas,
Jenkovszky, L. L., Troshin, S. M., Tyurin, N. E.   +2 more
core   +1 more source

Critical phenomena in N=4 SYM plasma

, 2010
Strongly coupled N=4 supersymmetric Yang-Mills plasma at finite temperature and chemical potential for an R-symmetry charge undergoes a second order phase transition. We demonstrate that this phase transition is of the mean field theory type.
Aharony, Alex Buchel, Balasubramanian, Behrndt, Benincasa, Benincasa, Buchel, Buchel, Buchel, Buchel, Buchel, Buchel, Buchel, Buchel, Buchel, Buchel, Cai, Cherman, Cvetič, Evans, Hohenberg, Hohler, Kovtun, Liu, Maeda, Maldacena, Maldacena, Onuki, Pilch, Policastro, Son   +30 more
core   +1 more source

CRITICAL PHENOMENA IN FINITE SYSTEMS [PDF]

Nucleus–Nucleus Collisions, 2001
Proceedings Bologna 2000 conference, M.Bruno et al. eds., World Sci. (in press)
Bonasera, A., Maruyama, T., Chiba, S.
openaire   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Critical Phenomena in Gravitational Collapse

Living Reviews in Relativity, 1999
As first discovered by Choptuik, the black hole threshold in the space of initial data for general relativity shows both surprising structure and surprising simplicity.
Gundlach Carsten
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Critical Dynamics Mediate Learning of New Distributed Memory Representations in Neuronal Networks

Entropy, 2019
We explore the possible role of network dynamics near a critical point in the storage of new information in silico and in vivo, and show that learning and memory may rely on neuronal network features mediated by the vicinity of criticality.
Quinton M. Skilling, Nicolette Ognjanovski, Sara J. Aton, Michal Zochowski   +3 more
doaj   +1 more source