Results 111 to 120 of about 15,117,675 (273)

Laser-Assisted Diamond Turning for Anisotropy Suppression in Calcium Fluoride

Micromachines
This paper proposes the use of laser-assisted cutting technology to control the brittle–plastic transition of single-crystal CaF2 through local thermal softening, thereby suppressing its processing anisotropy.
Enbo Xing, Jinsong Xue, Rongbiao Yang, Mingyue Wang, Huimin Zhou, Guohui Xing, Jianglong Li, Jiamin Rong, Huanfei Wen, Jun Tang, Jun Liu   +10 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Lightweight SiBCN-modified carbon-bonded carbon fiber composites with directional heat-leading function for efficient thermal protection

Journal of Advanced Ceramics
Hypersonic vehicles are subjected to critical aerodynamic heating during flight, which poses a substantial challenge for the design of thermal protection systems (TPSs).
Xinqiao Wang, Wentao Wu, Yan Zhang, Baolu Shi, Bin Ma, Xiaoguang Luo, Ning Zhou, Baosheng Xu   +7 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Quantitative Review of Critical Plane Criteria and Stress Analysis Approaches for Multiaxial Fatigue of Welded Joints

Fatigue & Fracture of Engineering Materials & Structures
ABSTRACT This quantitative review evaluates the effectiveness of stress‐based critical plane criteria, specifically Findley's criterion, the approach due to Carpinteri–Spagnoli (CS), and the Modified Wöhler Curve Method (MWCM), in assessing fatigue strength in aluminum and steel welded joints subjected to constant amplitude (CA) and ...
Ng, C.T., Susmel, L.
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Multiaxial endurance limit estimation in notched structural components using a combined critical point-critical plane approach

, 2007
A high-cycle multiaxial fatigue criterion, based on a combined critical point-critical plane approach, is used to estimate the multiaxial endurance limit in notched metal structural components.
CARPINTERI, Andrea, DANILO VIAPPIANI, SPAGNOLI, Andrea, VANTADORI, Sabrina   +3 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Life assessment of welded joints using a critical plane approach

, 2017
In the present work the Fatemi-Socie approach is adopted in order to evaluate the fatigue strength of welded joints. This critical plane criterion has achieved good results in the nucleation life prediction concerning plain or notched components, however
Bertini, L., Fatemi, A., Marulo, G., Frendo, F.   +3 more
core