Results 101 to 110 of about 1,093,244 (310)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Fatigue assessment of a FSAE car rear upright by a closed form solution of the critical plane method

open access: yesFracture and Structural Integrity
Material fatigue is extensively discussed and researched within scientific and industrial communities. Fatigue damage poses a significant challenge for both metallic and non-metallic components, often resulting in unexpected failures of in-service parts.
A. Chiocca   +4 more
doaj   +1 more source

Multiaxial Fatigue Lifetime Estimation Based on New Equivalent Strain Energy Damage Model under Variable Amplitude Loading

open access: yesCrystals
The largest normal stress excursion during contiguous turn time instants of the maximum torsional stress is presented as an innovative path-independent fatigue damage quantity upon the critical plane, which is further employed for characterizing fatigue ...
Zhi-Qiang Tao   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Multiaxial Fatigue Life Calculation Model for Engineering Components in Rolling-Sliding Contact

open access: yesMATEC Web of Conferences, 2018
Number of important engineering components and elements such as gears, rollers, bearings operate in conditions of rolling-sliding contact loading. Determination of fatigue lives of such components and elements is very important for engineering practice ...
Basan Robert, Marohnić Tea
doaj   +1 more source

Single-domain versus two-domain configuration in thin ferromagnetic prisms

open access: yes, 2006
Thin ferromagnetic elements in the form of rectangular prisms are theoretically investigated in order to study the transition from single-domain to two-domain state, with changing the in-plane aspect ratio p.
Aharoni   +19 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Yang-Lee zeros and the critical behavior of the infinite-range two- and three-state Potts models

open access: yes, 2013
The phase diagram of the two- and three-state Potts model with infinite-range interactions, in the external field is analyzed by studying the partition function zeros in the complex field plane.
Glumac, Zvonko, Uzelac, Katarina
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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