Results 51 to 60 of about 15,117,675 (273)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Fatigue life prediction under mean stresses using critical plane approach
Abstract This paper suggests that multiaxial fatigue criteria can serve as damage parametersin the formulation of critical plane theory. We propose that by incorporatingstrain rate effects, critical plane approximation parameters can be effectivelyused to estimate fatigue life under various test conditions.
Simelia Dos Santos +1 more
openaire +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Comparative Analysis of Two Boundary Surface Constitutive Models for Sand Considering Particle Breakage [PDF]
To accurately consider the effect of particle breakage on the establishment of constitutive models for sand, one approach directly introduced the particle breakage ratio into a nonlinear critical state line (CSL) in the e-ln p plane, while another ...
GU Chenglong +3 more
doaj +1 more source
A Robust Control Approach to Understanding Nonlinear Mechanisms in Shear Flow Turbulence [PDF]
A robust control framework is used to investigate a streamwise constant projection of the Navier Stokes equations for plane Couette flow. Study of this streamwise constant model is motivated by both numerical and experimental observations that suggest ...
Gayme, Dennice F. Maynard
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

