Results 61 to 70 of about 11,033,430 (362)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
The critical end point of QCD [PDF]
Proceedings of XXIIIrd International Symposium on Lattice Field Theory — PoS(LAT2005), 2005 We investigate the critical end point of QCD with two flavours of light dynamical quarks at finite lattice cutoff a=1/4T using a Taylor expansion of the baryon number susceptibility. We find a strong volume dependence of the position of the critical end point.
Rajiv V. Gavai, Sourendu Gupta
openaire +4 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Condensed Matter Physics, 2010 The present work is devoted to the investigation of the 3D Ising-like model in the presence of an external field in the vicinity of critical point. The method of collective variables is used. General expressions for the order parameter and susceptibility
M.P. Kozlovskii, R.V. Romanik
doaj +1 more source
Big Bang as a Critical Point [PDF]
Advances in High Energy Physics, 2017 This article addresses the issue of possible gravitational phase transitions in the early universe. We suggest that a second-order phase transition observed in the Causal Dynamical Triangulations approach to quantum gravity may have a cosmological relevance.
openaire +5 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Phenomenological Consequences of Enhanced Bulk Viscosity Near the QCD Critical Point [PDF]
, 2016 In the proximity of the QCD critical point the bulk viscosity of quark-gluon matter is expected to be proportional to nearly the third power of the critical correlation length, and become significantly enhanced.
A. Monnai, S. Mukherjee, Y. Yin
semanticscholar +1 more source
Evidence for a Disordered Critical Point in a Glass-Forming Liquid. [PDF]
Physical Review Letters, 2015 Using computer simulations of an atomistic glass-forming liquid, we investigate the fluctuations of the overlap between a fluid configuration and a quenched reference system. We find that large fluctuations of the overlap develop as temperature decreases,
L. Berthier, R. Jack
semanticscholar +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source