Results 81 to 90 of about 2,430,844 (266)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Existence of solutions for a two-point boundary-value problem of a fourth-order Sturm-Liouville type

open access: yesElectronic Journal of Differential Equations, 2012
In this work, we establish the existence of two intervals for a parameter $lambda$ for which a two-point boundary-value problem of fourth-order Sturm-Liouville type admits three weak solutions whose norms are uniformly bounded with respect to $lambda$.
Shapour Heidarkhani
doaj  

Temperature Dependence of Optical Properties of MoS2 and WS2 Heterostructures Assessed by Spectroscopic Ellipsometry

open access: yesNanomaterials
We report the complex dielectric function ε = ε1 + iε2 of MoS2/WS2 and WS2/MoS2 heterostructures and their constituent monolayers MoS2 and WS2 for an energy range from 1.5 to 6.0 eV and temperatures from 39 to 300 K.
Hoang Tung Nguyen   +7 more
doaj   +1 more source

Indications of a ferromagnetic quantum critical point in [Formula: see text]. [PDF]

open access: yesSci Rep, 2023
Holmes-Hewett WF   +6 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Analysis of Shell Egg Pasteurization Using Computational Fluid Dynamics

open access: yesApplied Sciences
In the present work, the thermal pasteurization process of shell eggs was studied through Computational Fluid Dynamics. For large-size eggs (63–72 g), the required heating times at several different heating medium (water) temperatures, namely 54, 56, 58,
Pavlos-Antonios Sampanis   +3 more
doaj   +1 more source

critical point [PDF]

open access: yes, 2014
Citation: 'critical point' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01396 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Critical point for membrane bilayer formation. [PDF]

open access: yesBiochim Biophys Acta Biomembr, 2023
Gershfeld NL, Nossal R.
europepmc   +1 more source

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