Results 101 to 110 of about 10,934,305 (297)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Existence of solutions for a two-point boundary-value problem of a fourth-order Sturm-Liouville type

open access: yesElectronic Journal of Differential Equations, 2012
In this work, we establish the existence of two intervals for a parameter $lambda$ for which a two-point boundary-value problem of fourth-order Sturm-Liouville type admits three weak solutions whose norms are uniformly bounded with respect to $lambda$.
Shapour Heidarkhani
doaj  

Temperature Dependence of Optical Properties of MoS2 and WS2 Heterostructures Assessed by Spectroscopic Ellipsometry

open access: yesNanomaterials
We report the complex dielectric function ε = ε1 + iε2 of MoS2/WS2 and WS2/MoS2 heterostructures and their constituent monolayers MoS2 and WS2 for an energy range from 1.5 to 6.0 eV and temperatures from 39 to 300 K.
Hoang Tung Nguyen   +7 more
doaj   +1 more source

Indications of a ferromagnetic quantum critical point in [Formula: see text]. [PDF]

open access: yesSci Rep, 2023
Holmes-Hewett WF   +6 more
europepmc   +1 more source

critical point [PDF]

open access: yes, 2014
Citation: 'critical point' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01396 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Analysis of Shell Egg Pasteurization Using Computational Fluid Dynamics

open access: yesApplied Sciences
In the present work, the thermal pasteurization process of shell eggs was studied through Computational Fluid Dynamics. For large-size eggs (63–72 g), the required heating times at several different heating medium (water) temperatures, namely 54, 56, 58,
Pavlos-Antonios Sampanis   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Critical point for membrane bilayer formation. [PDF]

open access: yesBiochim Biophys Acta Biomembr, 2023
Gershfeld NL, Nossal R.
europepmc   +1 more source

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