Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
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Critical-point theory with applications to asymptotically linear wave and beam equations [PDF]
, 2000 Thomas Bartsch, Y. H. Ding
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
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THE OBJECTIVE HERMENEUTIC'S METHODOLOGY IN EDUCATION: AN EMANCIPATORY ANALYSIS IN THE POINT OF VIEW OF CRITICAL SOCIAL THEORY [PDF]
, 2022 Miriam Salomão, Marsiel Pacífico
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Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
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A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
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A perspective on the contributions of Alan C. Lazer to critical point theory
Electronic Journal of Differential Equations, 2000 Over the last thirty five years Professor Alan C. Lazer has been a leading figure in the development of min-max methods and critical point theory for applications to partial differential equations.
Alfonso Castro
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Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
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Infinite dimensional extensions of the Landesman-Lazer theorem
Electronic Journal of Differential Equations, 2021 Martin Schechter
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SOME REMARKS ON CRITICAL POINT THEORY FOR LOCALLY LIPSCHITZ FUNCTIONS Work performed under the auspices of G.N.A.M.P.A. of I.N.D.A.M. and partially supported by M.I.U.R. of Italy, 2001. [PDF]
, 2003 Giuseppina Barletta, S. Marano
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