Results 91 to 100 of about 5,657,828 (286)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Universality Classes of Critical Points in Constrained Glasses

, 2013
We analyze critical points that can be induced in glassy systems by the presence of constraints. These critical points are predicted by the Mean Field Thermodynamic approach and they are precursors of the standard glass transition in absence of ...
Franz, Silvio, Parisi, Giorgio
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Gradient Flow Line Near Birth-Death Critical Points [PDF]

, 1924
Near a birth-death critical point in a one-parameter family of gradient flows, there are precisely two Morse critical points of index difference one on the birth side.
Antony, Charel
core   +3 more sources

Non Mean-Field Quantum Critical Points from Holography

, 2010
We construct a class of quantum critical points with non-mean-field critical exponents via holography. Our approach is phenomenological. Beginning with the D3/D5 system at nonzero density and magnetic field which has a chiral phase transition, we ...
E. Witten, E. Witten, J. M. Maldacena, K.-Y. Kim, Keun-Young Kim, Kristan Jensen, Nick Evans, V. L. Berezinskii   +7 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Critical points of locally Lipschitz functionals inside and outside the ordered interval

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, under the condition that there exists an ordered interval composed of two internal ordered intervals which have the location similar to that of Amann's three-solution theorem, we add some simple conditions and then we obtain some results ...
Xi'an Xu, Baoxia Qin
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Multiple solutions of second order Hamiltonian systems

Electronic Journal of Qualitative Theory of Differential Equations, 2017
The existence and the multiplicity of periodic solutions for a parameter dependent second order Hamiltonian system are established via linking theorems. A monotonicity trick is adopted in order to prove the existence of an open interval of parameters for
Gabriele Bonanno, Roberto Livrea, Martin Schechter   +2 more
doaj   +1 more source

DAVIES CRITICAL POINT AND TUNNELING [PDF]

International Journal of Modern Physics D, 2012
From the point of view of tunneling, the physical meaning of the Davies critical point of a second-order phase transition in the black hole thermodynamics is clarified. At the critical point, the nonthermal contribution vanishes so that the black hole radiation is entirely thermal. It separates two phases: one with radiation enhanced by the nonthermal
openaire   +3 more sources