Results 81 to 90 of about 1,797,780 (305)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Rigidity-induced critical points
International audienceWhile classical theory of phase transitions deals with systems in which shape variation is energetically neutral, the account of rigidity can lead to the emergence of new thermodynamic features.
Truskinovsky, L, Grabovsky, Y
core +2 more sources
Critical-Points (Azeotropic Compositions) in Multicomponent Copolymerization
The necessary and sufficient conditions for the existence of critical points ( azeotropic compositions) in multicomponent copolymerization are defined, and the preferred method for calculating critical points for a given set of reactivity ratios is ...
G Moad +3 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Pairs of paths and critical points
Two sufficient conditions are presented, in terms of the values taken by a holomorphic function f(z) on a pair of smooth paths intersecting at a point z0 in its domain, implying that f′(z0)=0.
Florin Caragiu, Ioana Caragiu
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Infinitely many periodic solutions of nonlinear wave equations on $S^n$
The existence of time periodic solutions of nonlinear wave equations $$ u_{tt} - Delta_n u + ig(frac{n-1}{2}ig)^2u= g(u) - f(t, x) $$ on $n$-dimensional spheres is considered. The corresponding functional of the equation is studied by the convexity
Jintae Kim
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Solitary waves for the coupled nonlinear Klein-Gordon and Born-Infeld type equations
In this article we study the existence of solutions for a nonlinear Klein-Gordon-Maxwell equation coupled with a Born-Infeld equation.
Feizhi Wang
doaj

