Results 121 to 130 of about 8,524,171 (298)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Collective excitations of germinating pollen grains at critical points. [PDF]

Sci Rep, 2023
Pietruszka MA.
europepmc   +1 more source

Nontrivial critical points for asymptotically quadratic function

, 1992
In this paper we study the existence of nontrivial critical points. As applications, we study the existence of nontrivial solutions of the Dirichelet problem for nonlinear elliptic PDE and periodic boundary value problem for nonlinear ...
Liu, J.Q, Shujie, Li
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

GROSS REGIONAL PRODUCT AS AN INDICATOR OF ECONOMIC SECURITY IN THE RUSSIAN ARCTIC

Север и рынок: формирование экономического порядка
The growing interest in economic security reflects the rising number of threats and challenges facing the modern world. Within this field, particular attention is devoted to methods for assessing economic security.
Galina V. Kobylinskaya
doaj   +1 more source

Ethical content in artificial intelligence systems: A demand explained in three critical points. [PDF]

Front Psychol, 2023
Bertoncini ALC, Serafim MC.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Thermodynamic stability and critical points in multicomponent mixtures with structured interactions. [PDF]

Phys Rev Res, 2022
Graf IR, Machta BB.
europepmc   +1 more source

Article from Pencil Points, March 1922

, 1922
Two page typed article from "Pencil Points" on Rice Institute, Department of Architecture letterhead stationery, describing the "Baile Espanole," the first Archi-Arts ball, held on February 3, 1922, at Autry ...
Pencil points
core