Bifid cardiac apex and spongiform cardiomyopathy in fetus with small microdeletion 16p12.2 of paternal origin. Critical points in family communication on 16p12.2 microdeletion. [PDF]
Clin Case Rep, 2023 Stabile M +4 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Neurocognition and hypothyroidism: Critical points
Annals of Indian Psychiatry, 2017 Avinash De Sousa, Amresh Shrivastava
doaj +1 more source
Periodic solutions for a class of second-order Hamiltonian systems
Electronic Journal of Differential Equations, 2005 Multiplicity results for an eigenvalue second-order Hamiltonian system are investigated. Using suitable critical points arguments, the existence of an exactly determined open interval of positive eigenvalues for which the system admits at least three ...
Gabriele Bonanno, Roberto Livrea
doaj
Medical cannabis: Critical points for clinical application [PDF]
Biomedica, 2022 Gómez-García DM, García-Perdomo HA.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Existence of standing waves for Schrodinger equations involving the fractional Laplacian
Electronic Journal of Differential Equations, 2017 We study a class of fractional Schrodinger equations of the form $$ \varepsilon^{2\alpha}(-\Delta)^\alpha u+ V(x)u = f(x,u) \quad\text{in } \mathbb{R}^N, $$ where $\varepsilon$ is a positive parameter, $0 < \alpha < 1$, $2\alpha < N$, $(-\Delta ...
Everaldo S. de Medeiros +2 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
[Prostate Imaging Reporting and Data System (PI-RADS) v 2.1: Overview and Critical Points]. [PDF]
J Korean Soc Radiol, 2023 Kim CK.
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source