The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Localization Properties of a Quasiperiodic Ladder under Physical Gain and Loss: Tuning of Critical Points, Mixed-Phase Zone and Mobility Edge. [PDF]
Materials (Basel), 2022 Roy S +4 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Predicting Activation Barriers With Ring and Bond Critical Points in the Kemp Elimination Reaction. [PDF]
ChemphyschemRedmon H +3 more
europepmc +1 more source
Critical Points of a Map to a Circle [PDF]
Proceedings of the National Academy of Sciences, 1939 openaire +3 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Rational Function with Two Critical Points
, 2001 Animation of f(x) = x/(x^2 + c) with c varying from -4 to 4.
Herman, Russell; Lugo, Gabriel
core +1 more source
Critical points and syzygies for Feynman integrals. [PDF]
J High Energy PhysPage B, Song Q.
europepmc +1 more source
Merging boundary critical points of a Morse function [PDF]
In 2015, Borodzik, Némethi and Ranicki proved that an interior critical point can be pushed to the boundary, where it splits into two boundary critical points.
Mielniczuk, Marcin, Borodzik, Maciej
core