Results 171 to 180 of about 1,797,780 (305)

Universality of pseudo-Goldstone damping near critical points. [PDF]

Nat Commun
Tan YY, Chen YR, Fu WJ, Li WJ.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Under ONIOM Layers: Analysis of BCR-ABL Enzyme Inhibitors Through Bond-Critical Points and Natural Orbitals. [PDF]

Molecules
Rocha KML, Nascimento ÉCM, Martins JBL.
europepmc   +1 more source

Critical Points of a Map to a Circle [PDF]

Proceedings of the National Academy of Sciences, 1939
openaire   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Evolution of entanglement entropy at SU(N) deconfined quantum critical points. [PDF]

Sci Adv
Song M, Zhao J, Cheng M, Xu C, Scherer M, Janssen L, Meng ZY.   +6 more
europepmc   +1 more source

Critical Points on the Use of Biologicals in Allergic Diseases and Asthma. [PDF]

Allergy Asthma Immunol Res, 2020
Agache I, Cojanu C, Laculiceanu A, Rogozea L.   +3 more
europepmc   +1 more source

Exploring the critical points of teaching STEM subjects in the time of COVID 19: the experience of the course "Microscopy Techniques for Forensic Biology". [PDF]

F1000Res, 2021
Brunelli E, Macirella R.
europepmc   +1 more source

Asymptotically critical points and their multiplicity

, 2002
In this paper we study multiplicity results for the critical points of a functional via topological information which ensures multiplicity of critical points for a sequence of approximating functionals. The main statement is quite simple, and it seems it
MUGNAI D., Mugnai, Dimitri, MARINO, ANTONIO   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source