Results 71 to 80 of about 847,794 (302)
Duality and free energy analyticity bounds for few-body Ising models with extensive homology rank [PDF]
, 2019 We consider pairs of few-body Ising models where each spin enters a bounded number of interaction terms (bonds) such that each model can be obtained from the dual of the other after freezing k spins on large-degree sites.
Dumer, Ilya +3 more
core +1 more source
Field theory of absorbing phase transitions with a non-diffusive conserved field [PDF]
, 2000 We investigate the critical behavior of a reaction-diffusion system exhibiting a continuous absorbing-state phase transition. The reaction-diffusion system strictly conserves the total density of particles, represented as a non-diffusive conserved field,
A. Chessa +32 more
core +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Agricultural Economics (AGRICECON), 2012 The tools and modern techniques used in the Design of Experiments (DOE) have been proved successful in meeting the challenge of continuous improvement of food and agricultural products over the last fifteen years.
Jan HRON
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The effect of Sustainable Land Management technologies on farming household food security in Kwara State, Nigeria [PDF]
Journal of Agricultural Sciences (Belgrade), 2019 Nigeria is among countries of the world confronted with the food insecurity problem. The agricultural production systems that produce food for the teeming population are not sustainable.
Salau Shehu A. +2 more
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Recent advances in 3D printing of biomaterials. [PDF]
, 2015 3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of ...
Chia, Helena N, Wu, Benjamin M
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source