Results 91 to 100 of about 849,758 (304)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Elucidation of the Nano-Mechanical Property Evolution of 3D-Printed Zirconia

Micro
Understanding the mechanical properties of three-dimensional (3D)-printed ceramics while keeping the parts intact is crucial for advancing their application in high-performance and biocompatible fields, such as biomedical and aerospace engineering.
Joshua Z. R. Dantzler, Diana Hazel Leyva, Amanda L. Borgaro, Md Shahjahan Mahmud, Alexis Lopez, Saqlain Zaman, Sabina Arroyo, Yirong Lin, Alba Jazmin Leyva   +8 more
doaj   +1 more source

Development of a viable concrete printing process [PDF]

, 2011
A novel Concrete Printing process has been developed, inspired and informed by advances in 3D printing, which has the potential to produce highly customised building components.
Alistair Gibb, How To Cite, Rene Wackrow, Richard Buswell, Simon Austin, Sungwoo Lim, Thanh Le, Tony Thorpe   +7 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Tailoring Patient-Specific Cranial Implants for Bone Reconstruction via End-to-End Deep Learning Image-to-Print Approach

IEEE Access
Timely, patient-specific cranial implants are critical for restoring skull integrity after trauma, accidents or surgery, yet off-the-shelf devices arrive in coarse, fixed size increments that often fail to match irregular defects.
Mahmoud Salem, Omar Wael, Moataz M. Attallah, Ahmed Elkaseer   +3 more
doaj   +1 more source

Online Interventions for Social Marketing Health Behavior Change Campaigns: A Meta-Analysis of Psychological Architectures and Adherence Factors

Journal of Medical Internet Research, 2011
BackgroundResearchers and practitioners have developed numerous online interventions that encourage people to reduce their drinking, increase their exercise, and better manage their weight.
Cugelman, Brian, Thelwall, Mike, Dawes, Phil   +2 more
doaj   +1 more source

Critical Behavior of the Random Potts Chain

, 1999
We study the critical behavior of the random q-state Potts quantum chain by density matrix renormalization techniques. Critical exponents are calculated by scaling analysis of finite lattice data of short chains ($L \leq 16$) averaging over all possible ...
A. Aharony, A. B. Harris, A. Juozapavic̆ius, A. P. Young, B. Berche, B. Derrida, B. M. McCoy, B. M. McCoy, B. M. McCoy, B. N. Shalaev, C. Chatelain, C. Chatelain, C. Chatelain, D. S. Fisher, E. Carlon, E. Carlon, F. Iglói, F. Iglói, J. B. Kogut, J. L. Cardy, J. L. Jacobsen, K. Hui, M. Aizenman, M. De Menech, M. Henkel, M. Henkel, N. V. Prokof’ev, S. R. White, S. R. White, S. Wiseman, S. Wiseman, T. Nishino, T. Senthil, T. W. Burkhardt, V. S. Dotsenko, W. Selke, Y. Imry   +36 more
core   +1 more source

Mesenchymal stem cell seeded, biomimetic 3D printed scaffolds induce complete bridging of femoral critical sized defects

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2018
AbstractNo current clinical treatments provide an ideal long‐term solution for repair of long bone segment defects. Incomplete healing prevents patients from returning to preinjury activity and ultimately requires additional surgery to induce healing. Obtaining autologous graft material is costly, incurs morbidity, requires surgical time, and quality ...
John A, Szivek, David A, Gonzales, Andrew M, Wojtanowski, Michael A, Martinez, Jordan L, Smith   +4 more
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Pneumatic dispensing of aqueous Al₂O₃ suspensions via material extrusion additive manufacturing

Next Materials
Material extrusion, also known as Robocasting or Direct Ink Writing (DIW) is an efficient and eco-friendly additive manufacturing method for fabricating large and thick ceramic components, such as alumina.
Flavie Lebas, Sylvain Marinel, Christelle Bilot, Romuald Herbinet, Loïc Le Pluart, Charles Manière   +5 more
doaj   +1 more source