Results 101 to 110 of about 12,108,841 (318)
3D printed CoCrMo personalised load-bearing meta-scaffold for critical size tibial reconstruction
Annals of 3D Printed MedicinePorous scaffolds have evolved, allowing personalised 3D-printed structures that can improve tissue reconstruction. By using scaffolds with specific porosity, Poisson's ratio and stiffness, load-bearing tissues such as tibial reconstruction can be improved.
Chameekara T. Wanniarachchi +7 more
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Elucidation of the Nano-Mechanical Property Evolution of 3D-Printed Zirconia
MicroUnderstanding the mechanical properties of three-dimensional (3D)-printed ceramics while keeping the parts intact is crucial for advancing their application in high-performance and biocompatible fields, such as biomedical and aerospace engineering.
Joshua Z. R. Dantzler +8 more
doaj +1 more source
Journal of Functional BiomaterialsRapid vascularization is essential for bone regeneration in oral and maxillofacial surgery. This systematic review synthesised in vivo evidence on 3D-printed composite scaffolds in rodent critical-size calvarial defects quantified by Microfil perfusion and micro-CT.
Milda Vitosyte +4 more
openaire +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
IEEE AccessTimely, patient-specific cranial implants are critical for restoring skull integrity after trauma, accidents or surgery, yet off-the-shelf devices arrive in coarse, fixed size increments that often fail to match irregular defects.
Mahmoud Salem +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Pneumatic dispensing of aqueous Al₂O₃ suspensions via material extrusion additive manufacturing
Next MaterialsMaterial extrusion, also known as Robocasting or Direct Ink Writing (DIW) is an efficient and eco-friendly additive manufacturing method for fabricating large and thick ceramic components, such as alumina.
Flavie Lebas +5 more
doaj +1 more source